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Contrary to earlier studies, a National Institutes of Health funded analysis of records from more than 88,000 pregnancies in which women took the anti-nausea drug ondansetron found no increased risk for newborn heart malformations and only a slightly increased risk for cleft lip and palate.

In 2018, researchers funded by NICHD made significant progress in advancing the health and well-being of infants, children, teenagers, and adults across the United States and around the world.

A first-time mother’s risk of pelvic floor disorders is strongly associated with how her baby is delivered, according to a study funded by the National Institutes of Health. Pelvic floor disorders are thought to result from weakening or injury of the muscles, ligaments and connective tissue in the lowest part of the pelvis.

Dr. Candace Tingen with NICHD’s Gynecological Health and Disease Branch speaks about the possibilities of tapping a woman’s menstrual cycle for signs of disease. Listen to our latest podcast.

Maternal adipokines—molecules produced by fat cells—influence fetal growth and newborn length, birthweight, and proportion of body fat.

The initiative seeks to improve treatment and care of infants and children who were exposed to opioids in the womb.

Infants and toddlers in low-income, rural areas may be at higher risk for second- and third-hand smoke than previously reported, according to an NIH-supported study.

In studies of mice and nonhuman primates, researchers funded by the National Institutes of Health have used a technique known as RNA interference to reduce high levels of a protein that can cause preeclampsia, a potentially fatal high blood pressure disorder of pregnancy.

A clinical trial funded by the National Institutes of Health will evaluate a male contraceptive gel for its ability to prevent pregnancy.

Researchers funded by the National Institutes of Health have produced human uterine endometrial cells from adult stem cells. The findings could lead to a way to produce new uterine cells from a patient’s own tissues, which could then be used to treat uterine disorders such as endometriosis, uterine factor infertility, and early-stage endometrial cancer.

Compared to younger mothers, mothers over 35 are at higher risk of death and serious illness if they conceive 6 months or less after the birth of a previous child, according to a study funded in part by the National Institutes of Health. For mothers of all ages, such short intervals between pregnancies were associated with higher risk for preterm birth and for having infants small for their gestation age.

Collaboration with CDC aimed at evaluating pregnancy initiatives and outcomes

NIH findings in rodents suggest that astrocytes play an important role in how the brain processes information.

Dr. Kathleen Egan and her son David Egan, pioneers of inclusion for people with Down syndrome, share their experiences. Listen.

PAT is a free resource incorporating placental data from publications and public databases into a single website for the research community.

Nearly a third of children experiencing a concussion had symptoms, including headache, irritability, and fatigue, up to a year after their injury, according to a study funded by the National Institutes of Health.

The brain’s pineal gland has two kinds of pinealocytes—cells that make melatonin—the hormone that regulates the body’s sleep and wake cycles, according to a rodent study conducted by researchers at the National Institutes of Health. The findings have the potential to inform future research on disorders that involve melatonin, such as jet lag and seasonal affective disorder.

Contrary to results from earlier studies, the vitamin-like substance myo-inositol does not appear to prevent a potentially blinding complication of preterm birth and may even reduce rates of survival among preterm infants, suggests a study funded by the National Institutes of Health.

NICHD’s mission includes understanding child development and behavior. Check out these scientific advances related to Attention Deficit/Hyperactivity Disorder.