NICHD conducts and supports a variety of clinical research projects related to maternal health and maternal morbidity and mortality.
- Maternal Newborn Health Registry (MNH)
The primary purpose of this study is to quantify and understand trends in pregnancy outcomes in low-resource areas over time to provide population-based data on stillbirths and neonatal and maternal mortality.
- Biomarkers in Obstetrical Complications
The goal of this study is to develop predictive models to identify women who may be at risk for developing pregnancy complications.
- Pravastatin for Prevention of Preeclampsia (Statin)
The purpose of this study is to determine the pharmacokinetic parameters and collect preliminary safety data for pravastatin when used as a prophylactic daily treatment in pregnant women at high risk for preeclampsia.
- Tranexamic Acid for the Prevention of Obstetrical Hemorrhage After Cesarean (TXA)
The goal of this study is to assess whether tranexamic acid as prophylaxis lowers the risk of postpartum hemorrhage in women undergoing a cesarean delivery.
- Azithromycin-Prevention in Labor Use Study (A-PLUS)
This international trial is designed to test whether oral azithromycin administered during labor is effective in preventing infections and deaths in women and their newborns.
Select one of the following links to view ClinicalTrials.gov search results for studies on maternal mortality.