Dr. Bonifacino received his Ph.D. in Biochemistry from the University of Buenos Aires, Argentina. He was a post-doctoral fellow in the laboratory of Richard D. Klausner at NIDDK and NICHD, studying the mechanisms of assembly and quality control of multi-protein complexes in the endoplasmic reticulum. He rose through the ranks to his current position as Head of the Section on Intracellular Protein Trafficking, and Associate Scientific Director of the Neurosciences and Cellular and Structural Division, NICHD. His laboratory investigates the molecular mechanisms by which proteins are delivered to different intracellular compartments, and the diseases that result from dysfunction of these mechanisms. Specific projects include the study of coat proteins involved intracellular transport, polarized sorting in neurons, organelle positioning and motility, endosomal retrieval pathways, and neurodevelopmental disorders caused by defects in these processes.