MAS is a genetic disease that affects the bones, skin, and the production of certain hormones, including those that affect growth and the onset of puberty. NICHD supports research to understand the genetic causes of MAS, how it affects the body, and treatments for MAS and related conditions.
General Information
MAS is a genetic disorder that affects the skin, bones, and the production of certain hormones.
MAS symptoms can vary from mild to severe, and may include light-brown birthmarks, fibrous tissue in the bones, and early onset of puberty.
MAS is rare, affecting between 1 in every 100,000 to 1 million live births worldwide.
MAS is a genetic disorder, which means that a change, also called a mutation, in a gene causes it.
A person is diagnosed with MAS if he or she has a combination of symptoms, a few of which include light-brown birthmarks, bone irregularities, and early onset of puberty.
Treatment for MAS depends on the extent and the severity of a person’s symptoms. For example, healthcare providers may recommend medication for endocrine problems, or surgery for bone issues.
Research
NICHD conducts and supports research on MAS and on many disorders associated with MAS.
Find a Study
NICHD conducts and supports a variety of clinical research projects related to MAS.
BACK TO TOP