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Sample Applications & More

Several NIAID investigators have graciously agreed to share their exceptional applications and summary statements as samples to help the research community. Below the list of applications, you’ll also find example forms, sharing plans, letters, emails, and more. Find more guidance at NIAID’s Apply for a Grant.

Always follow your funding opportunity's instructions for application format. Although these applications demonstrate good grantsmanship, time has passed since these grantees applied. The samples may not reflect the latest format or rules. NIAID posts new samples periodically.

The text of these applications is copyrighted. Awardees provided express permission for NIAID to post these grant applications and summary statements for educational purposes. Awardees allow you to use the material (e.g., data, writing, graphics) they shared in these applications for nonprofit educational purposes only, provided the material remains unchanged and the principal investigators, awardee organizations, and NIH NIAID are credited.

Freedom of Information Act (FOIA). NIAID is strongly committed to protecting the integrity and confidentiality of the peer review process. When NIH responds to FOIA requests for grant applications and summary statements, the material will be subject to FOIA exemptions and include substantial redactions. NIH must protect all confidential commercial or financial information, reviewer comments and deliberations, and personal privacy information.

Note on Section 508 Conformance and Accessibility. We have reformatted these samples to improve accessibility for people with disabilities and users of assistive technology. If you have trouble accessing the content, please contact the NIAID Office of Knowledge and Educational Resources at deaweb@niaid.nih.gov.

Table of Contents

Find sample applications and summary statements below by type:

Find additional resources in the NIAID and NIH Sample Forms, Plans, Letters, Emails, and More section.

Research Grants

R01 Sample Applications and Summary Statements

The R01 is the NIH standard independent research project grant. An R01 is meant to give you four or five years of support to complete a project, publish, and reapply before the grant ends. Read more at NIAID’s Comparing Popular Research Project Grants: R01, R03, and R21.

R01 Samples Using Forms Version D
PI and Grantee Institution Application Resources
Vernita Gordon, Ph.D., of the University of Texas at Austin
“Assessing the roles of biofilm structure and mechanics in pathogenic, persistent infections” (Forms-D)
Full Application
Summary Statement
Monica Gandhi, M.D., of the University of California, San Francisco
“Hair Extensions: Using Hair Levels to Interpret Adherence, Effectiveness and Pharmacokinetics with Real-World Oral PrEP, the Vaginal Ring, and Injectables” (Forms-D)
Full Application
Summary Statement
Tom Muir, Ph.D., of Princeton University
"Peptide Autoinducers of Staphylococcal Pathogenicity" (Forms-D)
Full Application
Summary Statement
R01 Samples Using Forms Version C
PI and Grantee Institution Application Resources
William Faubion, Ph.D., of the Mayo Clinic Rochester
“Inflammatory cascades disrupt Treg function through epigenetic mechanisms” (Forms-C)
Full Application
Summary Statement
Chengwen Li, Ph.D., and Richard Samulski, Ph.D., of University of North Carolina at Chapel Hill
“Enhance AAV Liver Transduction with Capsid Immune Evasion” (Forms-C)
Full Application
Summary Statement
Mengxi Jiang, Ph.D., of University of Alabama at Birmingham
“Intersection of polyomavirus infection and host cellular responses” (Forms-C)
Full Application
Summary Statement

R03 Sample Applications and Summary Statements

The small grant (R03) supports new research projects that can be carried out in a short period of time with limited resources. They are awarded for up to two years and are not renewable. R03s are not intended for new investigators. Read more at NIAID’s Comparing Popular Research Project Grants: R01, R03, and R21.

PI and Grantee Institution Application Resources
Martin Karplus, Ph.D., of Harvard University
"Modeling atomic structure of the EmrE multidrug pump to design inhibitor peptides" (Forms-B2)
Full Application
Chad A. Rappleye, Ph.D., of Ohio State University
"Forward genetics-based discovery of Histoplasma virulence genes" (Forms-B2)
Full Application
Summary Statement

R15 Sample Applications and Summary Statements

The Research Enhancement Award (R15) program supports small-scale research projects to expose students to research and strengthen the research environment at educational institutions that have not been major recipients of NIH support. They are awarded for up to three years.

PI and Grantee Institution Application Resources

Artem Domashevskiy, Ph.D., of John Jay College of Criminal Justice
“Development of a Novel Inhibitor of Ricin: A Potential Therapeutic Lead against Deadly Shiga and Related Toxins” (Forms-D)

Full Application
Summary Statement

Rahul Raghavan, Ph.D., of Portland State University
"Elucidating the evolution of Coxiella to uncover critical metabolic pathways" (Forms-D)
Full Application
Summary Statement

R21 Sample Applications and Summary Statements

The R21 funds novel scientific ideas, model systems, tools, agents, targets, and technologies that have the potential to substantially advance biomedical research. R21s are not intended for new investigators, and there is no evidence that they provide a path to an independent research career. Read more at NIAID’s Comparing Popular Research Project Grants: R01, R03, and R21.

PI and Grantee Institution Application Resources
Steven W. Dow, D.V.M., Ph.D., of Colorado State University, Fort Collins
"Mechanisms of enteric Burkholderia psuedomallei infection" (Forms-B)
Full Application
Summary Statement
Joseph M. McCune, M.D., Ph.D., of the University of California, San Francisco
"Human immune system layering and the neonatal response to vaccines" (Forms-B)
Full Application
Summary Statement
Peter John Myler, Ph.D., and Marilyn Parsons, Ph.D., of the Seattle Biomedical Research Institute
"Ribosome profiling of Trypanosoma brucei" (Forms-B)
Full Application
Summary Statement
Howard T. Petrie, Ph.D., of Scripps Florida
"Lymphoid signals for stromal growth and organization in the thymus." (Forms-B)
Full Application
Summary Statement
Michael N. Starnbach, Ph.D., of Harvard University Medical School
"Alteration of host protein stability by Legionella" (Forms-B)
Full Application
Summary Statement

R21/R33 Sample Application and Summary Statement

The R21/R33 supports a two-phased award without a break in funding. It begins with the R21 phase for milestone-driven exploratory or feasibility studies with a possible transition to the R33 phase for expanded development. Transition to the second phase depends on several factors, including the achievement of negotiated milestones.

PI and Grantee Institution Application Resources
Stephen Dewhurst, Ph.D., of the University of Rochester
"The semen enhancer of HIV infection as a novel microbicide target" (Forms-B)
Full Application
Summary Statement

Small Business Grants

R41, R42, R43, and R44 – Small Business Sample Applications

The SBIR (R43/R44) and STTR (R41/R42) programs support domestic small businesses to engage in research and development with the potential for commercialization. Read more about NIAID Small Business Programs.

PI and Grantee Institution Application Resources
Iain James MacLeod, Ph.D., of Aldatu Biosciences, Inc.
“PANDAA for universal, pan-lineage molecular detection of Lassa fever infection.” (SBIR Phase I / R43, Forms-E)
Full Application
Summary Statement
Benjamin Delbert Brooks, Ph.D., of Wasatch Microfluidics
“High-throughput, multiplexed characterization and modeling of antibody:antigen binding, with application to HSV” (SBIR Phase I / R43, Forms-D)
Full Application
Summary Statement
Yingru Liu, Ph.D., of TherapyX, Inc.
“Experimental Gonococcal Vaccine” (SBIR Phase II / R44, Forms-D)
Full Application
Summary Statement
James Smith, Ph.D., of Sano Chemicals, Inc.
“Lead Compound Discovery from Engineered Analogs of Occidiofungin” (STTR Phase I / R41, Forms-D)
Full Application
Summary Statement
David H. Wagner, Ph.D., of OP-T-MUNE, Inc.
“Developing a small peptide to control autoimmune inflammation in type 1 diabetes" (STTR Phase I / R41, Forms-D)
Full Application
Summary Statement
Timothy C. Fong, Ph.D., of Cellerant Therapeutics, Inc.
"Novel indication for myeloid progenitor use: Induction of tolerance" (STTR Phase I / R41, Forms-B2)
Full Application
Jose M. Galarza, Ph.D., of Technovax, Inc.
"Broadly protective (universal) virus-like particle (VLP) based influenza vaccine" (SBIR Phase I / R43, Forms-B2)
Full Application
Michael J. Lochhead, Ph.D., of MBio Diagnostics, Inc.
"Point-of-Care HIV Antigen/Antibody Diagnostic Device" (SBIR Phase II / R44, Forms-B2)
Full Application
Kenneth Coleman, Ph.D., of Arietis Corporation
"Antibiotics for Recalcitrant Infection" (SBIR Fast-Track, Forms-B1)
Full Application
Patricia Garrett, Ph.D., of Immunetics, Inc.
"Rapid Test for Recent HIV Infection" (SBIR Phase II / R44, Forms-B1)
Full Application
Raymond Houghton, Ph.D., of InBios International, and David AuCoin, Ph.D., of University of Nevada School of Medicine
"Antigen Detection assay for the Diagnosis of Melioidosis" (STTR Phase II / R42, Forms-B1)
Full Application
Mark Poritz*, Ph.D., of BioFire Diagnostics, LLC.
"Rapid, automated, detection of viral and bacterial pathogens causing meningitis" (SBIR Phase I / R43, Forms-B1)
Full Application

*Dr. Mark Poritz submitted the original grant application. In the course of the first year of funding, Dr. Andrew Hemmert took on increasing responsibility for the work. For the grant renewal, Dr. Poritz proposed that Dr. Hemmert replace him as the PI.

Training and Career Awards


K01 Sample Applications and Summary Statements

The Research Scientist Development Award (K01) supports those with a research or health-professional doctoral degree and research development plans in epidemiology, computational modeling, or outcomes research. Read more about NIAID Career Development Awards (K).

PI and Grantee Institution Application Resources

Lilliam Ambroggio, Ph.D., of the Cincinnati Children’s Hospital Medical Center
“Metabolomics Evaluation of the Etiology of Pneumonia” (Forms-D)

Full Application
Summary Statement

Peter Rebeiro, Ph.D., of the Vanderbilt University Medical Center
"The HIV Care Continuum and Health Policy: Changes through Context and Geography" (Forms-D)
Full Application
Summary Statement

K08 Sample Applications and Summary Statements

The Mentored Clinical Scientist Research Career Development Award (K08) supports those with current work in biomedical or behavioral research, including translational research, a clinical doctoral degree such as M.D., D.V.M., or O.D., and a professional license to practice in the United States. Read more about NIAID Career Development Awards (K).

PI and Grantee Institution Application Resources
Lenette Lu, M.D., Ph.D., of the Massachusetts General Hospital
“Antibody Mediated Mechanisms of Immune Modulation in Tuberculosis” (Forms-D)
Full Application
Summary Statement
Tuan Manh Tran, M.D., Ph.D., of the Indiana University-Purdue University at Indianapolis
“Defining clinical and sterile immunity to Plasmodium falciparum infection using systems biology approaches” (Forms-D)
Full Application
Summary Statement

F31 Sample Applications and Summary Statements

National Research Service Award (NRSA) individual fellowship (F31) grants provide research experience to predoctoral scientists. Read more about NIAID Fellowship Grants (F).

PI and Grantee Institution Application Resources
Nicole Putnam, Ph.D., of Vanderbilt University
“The impact of innate immune recognition of Staphylococcus aureus on bone homeostasis and skeletal immunity”

Full Application
Summary Statement

Nico Contreras, Ph.D., of University of Arizona
"The Immunological Consequences of Mouse Cytomegalovirus on Adipose Tissue"

Full Application
Summary Statement

Samantha Lynne Schwartz, Ph.D., of Emory University
“Regulation of 2'-5'-oligoadenylate synthetase 1 (OAS1) by dsRNA”

Full Application
Summary Statement

G11 Sample Applications and Summary Statements

The Extramural Associate Research Development Award (EARDA) (G11) provides funds to institutions eligible to participate in the NIH Extramural Associates Program for establishing or enhancing an office of sponsored research and for other research infrastructure needs. Search for NIAID G11 Opportunities.

PI and Grantee Institution Application Resources
Oye Nana Akuffo, M.B.A., of the Noguchi Memorial Institute for Medical Research, University of Ghana, Legon 
“Capacity Building for Enhanced Research Administration (CaBERA- II) in Africa” (Forms-E)
 
Full Application
Summary Statement
Andres Jaramillo Zuluaga, M.B.A., Centro Internacional de Entrenamiento e Investigaciones Medicas (CIDEIM)
“Implementing Strategies for Building Capacity in Research Administration at CIDEIM, and Subsequent Dissemination Within Colombia and the Latin American Region” (Forms-E) 
Full Application
Summary Statement
Stella Kakeeto, M.B.A., Makerere University
“Strengthening Makerere University's Research Administration Capacity for Efficient Management of NIH Grant Awards (SMAC)” (Forms-E)
Full Application
Summary Statement

U01 Sample Application and Summary Statement

The U01 research project cooperative agreement supports a discrete, specified, circumscribed project for investigators to perform in their areas of specific interest and competency. Learn more about NIAID Cooperative Agreements (U)

PI and Grantee Institution Application Resources
Aaron Meyer, Ph.D., of the University of California, Los Angeles
Falk Nimmerjahn, Ph.D., of Friedrich-Alexander University Erlangen-Nuremberg, Germany
"Mapping the effector response space of antibody combinations" (Forms-E)
Full Application
Summary Statement

NIAID and NIH Sample Forms, Plans, Letters, Emails, and More

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Have Questions?

A program officer in your area of science can give you application advice, NIAID's perspective on your research, and confirmation that NIAID will accept your application.

Find contacts and instructions at When to Contact an NIAID Program Officer.

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