News

A single oral dose of the antibiotic azithromycin can reduce the risk of postpartum sepsis and death among women who deliver vaginally by one-third, according to a large multi-country clinical trial funded by NICHD.

Computational analysis of the word usage in personal stories of recent birthing experiences can identify women likely to develop PTSD related to childbirth, suggests an NIH-funded study. The findings may aid development of a low-cost screening tool to help diagnose and treat childbirth-related PTSD.

Read about NICHD’s research findings and activities from 2022.

Researchers supported by the National Institutes of Health are launching a large study to evaluate a single dose of intravenous iron to treat women experiencing anemia after giving birth. The study will enroll nearly 5,000 women in Bangladesh, India, Pakistan, the Democratic Republic of Congo, Kenya, Zambia and Guatemala.

Compared to giving birth in 2019, giving birth in 2020 during the early stages of the pandemic was not associated with a higher risk of maternal death or a serious complication of pregnancy, suggests a study funded by the National Institutes of Health.

U.S. rates of pregnancy-associated homicide—deaths that occur among women who are pregnant or had been pregnant within one year—rose in 2020 during the COVID-19 pandemic, according to a recent NICHD-funded study.

Challenge competitions offer a mechanism to quickly bring in diverse voices and expertise to innovate and problem-solve. This month, NICHD and partners launched two challenges focused on improving our nation’s maternal health: the RADx® Tech for Maternal Health Challenge and the Connecting the Community for Maternal Health Challenge.

The National Institutes of Health is offering up to $8 million in cash prizes to accelerate development of technologies to improve maternal health outcomes for those who live in areas lacking access to maternity care.

The National Institutes of Health has launched a $3 million challenge competition to encourage community-based and advocacy organizations in the United States to develop the infrastructure and capabilities necessary to conduct maternal health research.

NIH recently released three funding opportunity announcements inviting applications for the Maternal Health Research Centers of Excellence initiative, which will develop and evaluate innovative approaches to reduce pregnancy-related complications and deaths and promote maternal health equity.

To help spur innovation against a growing maternal health crisis, NICHD launched the Decoding Maternal Morbidity Data Challenge last year. Learn about the winning proposals.

Life-threatening pregnancy complications known as severe maternal morbidity (SMM) appear to be associated with an increased length of hospital stay for infants and an increase in the cost of caring for them, suggests a study funded by the National Institutes of Health. The findings support the hypothesis that infants of mothers with SMM may also be at risk for severe complications. The authors concluded that helping patients to reduce their risk factors—in early pregnancy or before conception—may reduce the chances for SMM and improve the health of infants.

In the United States, more than 20 percent of deaths during pregnancy and the first year after childbirth are due to drug use, suicide, or homicide, an NICHD-funded study suggests. The number of pregnancy associated deaths from these causes increased between 2010 and 2019, with drug-related deaths nearly tripling.

Read about NICHD’s research findings and activities from 2021.

Pregnant women with disabilities have a much higher risk for severe pregnancy- and birth-related complications and death than other pregnant women, according to findings by researchers at the National Institutes of Health. Appearing in JAMA Network Open, the analysis of more than 223,000 deliveries in 19 U.S. hospitals found that roughly 2,199 women had a disability.

It just got easier to participate in the PregSource®: Crowdsourcing to Understand Pregnancy research project. The free app allows participants to track their weight, sleep, mood, and other features of their pregnancy in just a few taps.

Awarded projects seek to reduce pregnancy complications and prevent maternal deaths.

Dr. Grewal has been acting director of the division since February 2020.

Episodes of maternal stress or depression during pregnancy are associated with chemical modifications to placental genes, according to a study by researchers from the National Institutes of Health. The modifications involve DNA methylation—binding of compounds known as methyl groups to DNA—which can alter a gene’s activity. Some of the methylation changes associated with maternal depression occurred near genes involved in brain development, suggesting that maternal depression in pregnancy could have long-term implications for the mental development of the child.

NIH-supported program reduces maternal deaths, complications in rural Guatemalan communities.