Progress on Theme 2

Promoting Gynecologic, Andrologic, and Reproductive Health

Highlighted Programs and Activities

  • NEW: NICHD encourages small businesses to collaborate with scientists and clinicians in gynecologic health
    Through a small business RFA, NICHD supports collaborative research to develop, advance, and validate new devices and methods for non-invasive diagnosis and/or screening of endometriosis, adenomyosis, and/or uterine fibroids. Learn more: RFA-HD-21-020.
  • NEW: NICHD Centers to Advance Research in Endometriosis (CARE) program
    The recently launched CARE program will support basic, translational, and/or clinical studies to improve female reproductive health through successful prevention and treatment of endometriosis. Learn more: RFA-HD-21-002.
  • Intramural research: Pediatric and Adolescent Gynecology Program
    This program within the NICHD Division of Intramural Research integrates regional clinical care with a post-graduate training program. Participants can study gynecologic disorders that begin before puberty to understand both childhood and adult gynecologic disease and fertility.

Selected Recent Advances

  • Drug-containing nanoparticles reduce size of fibroid tumors in mice (PMID: 32632769)
    Researchers developed a prototype technique for shrinking uterine fibroids—sometimes painful, noncancerous tumors that form in and on the uterus. Researchers will now work to determine if the method is safe and effective for treating fibroids in people.
  • Zinc and folic acid supplementation do not improve male fertility (PMID: 31910279)
    Dietary supplements containing zinc and folic acid—marketed as a treatment for male infertility—did not improve pregnancy rates, sperm counts, or sperm function.
  • Satisfaction is high in preliminary study of male contraceptive pill (PMID: 32298717)
    Researchers testing a prototype “male pill” contraceptive method found that, in a preliminary study, 80 percent of participants were satisfied with the proposed method, which included taking up to four pills each day within 30 minutes of consuming a high-fat meal. More than one-half reported that they would use the method as their primary contraceptive if it were available. The findings indicate that a daily male contraceptive pill could be a satisfactory alternative to the female contraceptive pill for preventing pregnancy.
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