The National Institutes of Health will support a four-year follow-up study on the potential long-term effects of COVID-19 on women infected with SARS-CoV-2 during pregnancy. The study will also follow their offspring for any potential long-term effects.
News
NICHD issues News Releases and Media Advisories to the news media. Spotlight and Research Feature articles explain NICHD research findings and public health issues to the general public. An Item of Interest is a short announcement of relevant information, such as a notable staff change.
Director's Corner: Reflecting on Our Commitment to Nutrition Research
As we usher in November and Thanksgiving, it’s a fitting time to reflect on NICHD’s commitment to research on nutrition.
Media Advisory: NIH researchers link depression during pregnancy to placental gene modifications
Episodes of maternal stress or depression during pregnancy are associated with chemical modifications to placental genes, according to a study by researchers from the National Institutes of Health. The modifications involve DNA methylation—binding of compounds known as methyl groups to DNA—which can alter a gene’s activity. Some of the methylation changes associated with maternal depression occurred near genes involved in brain development, suggesting that maternal depression in pregnancy could have long-term implications for the mental development of the child.
Science Update: No serious adverse events from COVID-19 vaccine in breastfeeding women or their children, NIH-funded study suggests
No serious adverse events were reported by 180 breastfeeding women receiving either the Pfizer or Moderna vaccine, either among themselves or in their infants, according to a study funded by the National Institutes of Health. For the mothers, adverse events included muscle and body aches, fever and vomiting, pain, redness, swelling, or itching at the injection site.
Spotlight: Developing Mobile Health Solutions for Women in Guatemala
NIH-supported program reduces maternal deaths, complications in rural Guatemalan communities.
Release: NIH-funded study highlights stark racial disparities in maternal deaths
Racial and ethnic disparities in maternal mortality in the United States may be larger than previously reported, suggests an NICHD-funded study.
Release: NIH-funded study identifies benefits, risks of treatments for pregnancy of unknown location
Preemptive treatment for a nonviable pregnancy of unknown location resolves the condition more rapidly than treating symptoms as they arise, suggests an NICHD-supported study. However, both treatment approaches convey similar risks of adverse events.
Science Update: Lab-grown placental stem cells may yield insights into preeclampsia, NIH-funded study suggests
Preeclampsia—a life-threatening hypertensive disorder of pregnancy—may begin with a failure of the outermost cells of the early placenta to sufficiently invade the uterine wall, suggests a study funded by the National Institutes of Health. Researchers generated these outermost cells—known as trophoblasts—from stem cells taken from placentas of women who had preeclampsia during pregnancy.
Science Update: Fibroid risk associated with ancestry among Black and white women, NIH-funded study suggests
Among American Black and white women, the risk and extent of fibroids—benign tumors of the uterus—are associated with ancestry to distinct regions and populations, suggests a study funded by the National Institutes of Health. The study provides information that may lead to insights on the origins and treatments for these common tumors.
Release: NIH data challenge seeks innovative methods for identifying complication risks in first-time pregnancies
The National Institutes of Health will award up to $400,000 to individuals or groups who design an effective method for analyzing a large data set of first-time pregnancies and identifying risk factors for adverse outcomes, such as hypertensive disorders, diabetes and infection. A total of $50,000 will be awarded to each of seven winners designing the most effective means to analyze the data. An additional $10,000 will be awarded to the top five winners whose methods identify risk factors in disadvantaged populations.
Media Advisory: Prototype device may diagnose common pregnancy complications by monitoring placental oxygen
Researchers at the National Institutes of Health have developed a prototype device that could potentially diagnose pregnancy complications by monitoring the oxygen level of the placenta.
Media Advisory: Healthy diet before and during pregnancy linked to lower risk of complications, NIH study suggests
A healthy diet around the time of conception through the second trimester may reduce the risk of several common pregnancy complications, suggests a study by researchers at the National Institutes of Health.
Director's Corner: A Mother’s Day Message: Time for Action to Improve Maternal Health
NICHD Director Dr. Diana Bianchi is joined by NIH Office of Research on Women’s Health Director Dr. Janine Clayton in assessing the growing maternal health crisis in the United States and describing NIH’s efforts to address it.
Science Update: COVID vaccines in pregnancy boost maternal and newborn immunity, NIH-funded study suggests
Current vaccines to prevent COVID-19 are highly effective in producing antibodies in pregnant people, resulting in more antibodies than what is generated from a natural SARS-CoV-2 virus infection, according to a study funded by the National Institutes of Health. Moreover, antibodies produced after vaccination are present in breastmilk and travel across the placenta, indicating that vaccination during pregnancy will also confer immunity to newborns.
Director's Corner: Advancing Research to Understand, Treat, and Prevent Long COVID
For many COVID-19 patients, full recovery remains elusive even long after they should feel “better.” NIH recently announced research opportunities to understand COVID-19 long haulers, who have what researchers now refer to as Post-acute sequelae of SARS-CoV-2 infection (PASC). NICHD joins these opportunities while remaining focused on PASC patients within our audiences of interest—pregnant and lactating people, children, and those with disabilities.
Release: NIH funds study to evaluate remdesivir for COVID-19 in pregnancy
A new study funded by the National Institutes of Health will evaluate the effects of remdesivir in pregnant women who have been prescribed the drug to treat COVID-19. The study, which will be conducted at 17 sites in the continental United States and Puerto Rico, aims to determine how pregnant women metabolize the drug and whether there are any potential side effects.
Media Advisory: NIH calls for greater inclusion of pregnant and lactating people in COVID-19 vaccine research
Pregnant people need to be protected through research rather than from research, the authors contend.
Director's Corner: Including pregnant and lactating people in SARS-CoV-2 vaccine research
As the COVID-19 pandemic persists, SARS-CoV-2 vaccines offer the potential to halt the spread of the virus. Yet, we know very little about the effectiveness and safety of the vaccines during pregnancy.
Science Update: Hormonal IUD as effective as a copper IUD at emergency contraception and with less discomfort, NICHD-funded study suggests
A hormone-releasing intrauterine device (IUD) appears to be as effective at emergency contraception as a copper IUD, suggests a study funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The hormone-releasing IUD contains levonorgestrel, a synthetic form of the reproductive hormone progesterone. Compared to the copper IUD, the levonorgestrel IUD has been shown to reduce heavy bleeding and menstrual discomfort.
Media Advisory: Severe COVID-19 in pregnancy associated with preterm birth, other complications
NIH-funded study suggests mother-to-infant transmission appears to be rare