An individual’s risk for death by suicide may begin before they are born, suggests a study by researchers at the National Institutes of Health. The authors compared pregnancy and birth records of nearly 50,000 individuals born between 1959 and 1966 to death records through 2016. They found that suicide rates were higher for males, white people, and for those who were among the younger siblings in a family. Other risk factors included having a parent with less than a high school education, having a parent who worked a manual labor job, and having a mother with a high rate of pregnancy complications or who smoked during pregnancy.
News
NICHD issues News Releases and Media Advisories to the news media. Spotlight and Research Feature articles explain NICHD research findings and public health issues to the general public. An Item of Interest is a short announcement of relevant information, such as a notable staff change.
Media Advisory: Sleep-disordered breathing in early pregnancy linked to insulin resistance
Sleep-disordered breathing in early pregnancy is associated with insulin resistance or difficulty clearing glucose from the blood, suggests a small study funded by the National Institutes of Health. The results strengthen the link between sleep-disordered breathing, which includes pauses or slowing of breathing during sleep, and gestational diabetes. They also suggest that screening pregnant women, particularly those with overweight or obesity, for sleep-disordered breathing could identify those who might benefit from early interventions to reduce their diabetes risk.
Item of Interest: PregSource® Mobile App Allows Access from Anywhere
It just got easier to participate in the PregSource®: Crowdsourcing to Understand Pregnancy research project. The free app allows participants to track their weight, sleep, mood, and other features of their pregnancy in just a few taps.
Release: NIH announces winners of data challenge to identify risk factors for first-time pregnancies
Awarded projects seek to reduce pregnancy complications and prevent maternal deaths.
Item of Interest: Una Grewal Appointed Director of the Division of Population Health Research
Dr. Grewal has been acting director of the division since February 2020.
Spotlight: Developing Mobile Health Solutions for Women in Guatemala
NIH-supported program reduces maternal deaths, complications in rural Guatemalan communities.
Release: Eating habits change only slightly after gestational diabetes diagnosis, NIH study suggests
Pregnant women made only modest dietary changes after being diagnosed with gestational diabetes, according to a study by NICHD researchers.
Director's Corner: A Mother’s Day Message: Time for Action to Improve Maternal Health
NICHD Director Dr. Diana Bianchi is joined by NIH Office of Research on Women’s Health Director Dr. Janine Clayton in assessing the growing maternal health crisis in the United States and describing NIH’s efforts to address it.
Science Update: NIH-funded study raises possibility that outermost placental cells may halt spread of SARS-CoV-2
Trophoblasts—the outermost fetal cells of the placenta—may be able to contain SARS-CoV-2 and prevent it from spreading to the fetus even though these cells appear to be susceptible to infection by the virus, a study by NIH-funded researchers suggests. Further research into how trophoblasts might contain the virus could lead to ways to prevent COVID-19 in children and adults. The findings may also lead to insights on why fetuses are only rarely infected with SARS-CoV-2.
Media Advisory: New ultrasound technique detects fetal circulation problems in placenta
A team of researchers funded by the National Institutes of Health has developed a new ultrasound technique to monitor the placenta for impaired fetal blood flow early in pregnancy. The technique, which uses conventional ultrasound equipment, relies on subtle differences in the pulsation of fetal blood through the arteries at the fetal and placental ends of the umbilical cord, potentially enabling physicians to identify placental abnormalities that impair fetal blood flow and, if necessary, deliver the fetus early.
Science Update: COVID vaccines in pregnancy boost maternal and newborn immunity, NIH-funded study suggests
Current vaccines to prevent COVID-19 are highly effective in producing antibodies in pregnant people, resulting in more antibodies than what is generated from a natural SARS-CoV-2 virus infection, according to a study funded by the National Institutes of Health. Moreover, antibodies produced after vaccination are present in breastmilk and travel across the placenta, indicating that vaccination during pregnancy will also confer immunity to newborns.
Director's Corner: Advancing Research to Understand, Treat, and Prevent Long COVID
For many COVID-19 patients, full recovery remains elusive even long after they should feel “better.” NIH recently announced research opportunities to understand COVID-19 long haulers, who have what researchers now refer to as Post-acute sequelae of SARS-CoV-2 infection (PASC). NICHD joins these opportunities while remaining focused on PASC patients within our audiences of interest—pregnant and lactating people, children, and those with disabilities.
Release: NIH funds study to evaluate remdesivir for COVID-19 in pregnancy
A new study funded by the National Institutes of Health will evaluate the effects of remdesivir in pregnant women who have been prescribed the drug to treat COVID-19. The study, which will be conducted at 17 sites in the continental United States and Puerto Rico, aims to determine how pregnant women metabolize the drug and whether there are any potential side effects.
Media Advisory: NIH calls for greater inclusion of pregnant and lactating people in COVID-19 vaccine research
Pregnant people need to be protected through research rather than from research, the authors contend.
Director's Corner: Including pregnant and lactating people in SARS-CoV-2 vaccine research
As the COVID-19 pandemic persists, SARS-CoV-2 vaccines offer the potential to halt the spread of the virus. Yet, we know very little about the effectiveness and safety of the vaccines during pregnancy.
Media Advisory: Severe COVID-19 in pregnancy associated with preterm birth, other complications
NIH-funded study suggests mother-to-infant transmission appears to be rare
Science Update: Childbirth during COVID-19 pandemic associated with anxiety, post-traumatic stress symptoms, NIH-supported study suggests
Increased stress may interfere with adjustment to new motherhood, mother-infant bonding
Spotlight: Selected NICHD Research Advances of 2020
Read about NICHD’s research findings and activities from 2020.
Science Update: COVID-19 in third trimester may reduce level of SARS-CoV-2 antibodies transferred across the placenta
For pregnant women with COVID-19 in the third trimester, antibodies against the SARS-CoV-2 virus appear to be transferred to the fetus at lower levels, compared to antibodies against two other respiratory diseases, suggests a study funded by the National Institutes of Health. However, one type of antibody against SARS-CoV-2 was transferred to the fetus more efficiently than the other antibodies against the virus, raising the possibility of at least some immune protection against the disease for the newborn.
Release: Pregnant women in third trimester unlikely to pass SARS-CoV-2 infection to newborns
Pregnant women who are infected with SARS-CoV-2, the virus that causes COVID-19, during the third trimester are unlikely to pass the infection to their newborns, suggests an NIH-funded study.