In a mouse study, researchers funded by the National Institutes of Health have identified a potential non-hormonal contraceptive that men could take shortly before sexual activity and have fertility restored the next day. Researchers gave male mice a compound that temporarily disables soluble adenylyl cyclase, the enzyme essential for activating a sperm cell’s ability to swim and mature so that it can travel through the female reproductive tract and fertilize an egg.
NICHD issues News Releases and Media Advisories to the news media. Spotlight and Research Feature articles explain NICHD research findings and public health issues to the general public. An Item of Interest is a short announcement of relevant information, such as a notable staff change.
Media Advisory: Researchers identify compounds that could lead to an on-demand, short-term contraceptive for men
Selected NICHD Research Advances of 2022
Read about NICHD’s research findings and activities from 2022.
Director's Corner: Expanding Contraceptive Choices
A safe, highly effective, reversible method of male contraception would fill an important public health need. Additionally, multipurpose prevention technologies (MPTs)—products that prevent both pregnancy and sexually transmitted infections—would increase sexual and reproductive health options for both women and men. NICHD supports a broad range of contraceptive research, including efforts to develop male contraceptives and MPTs.
Spotlight: One year and counting: Male birth control study reaches milestone
Learn about an experimental male contracteptive gel called NES/T, which was developed in collaboration with NICHD and the Population Council.
Spotlight: Selected NICHD Research Advances of 2021
Read about NICHD’s research findings and activities from 2021.
Science Update: NIH scientists design a potential non-hormonal contraceptive for men
Mouse studies targeting gonadotropin regulated testicular helicase (GRTH) appear to be a promising approach.
Item of Interest: NICHD website seeks to foster contraceptive and infertility research
A new website offers reproductive health researchers a way to search for genes, proteins, and other molecules that could provide the basis for studies to develop new contraceptive methods and infertility treatments. The Contraceptive Infertility Target Database (CITDBase) is a free public resource developed by the Contraceptive Development Program in the NICHD’s Division of Population Health Research.
Science Update: Hormonal IUD as effective as a copper IUD at emergency contraception and with less discomfort, NICHD-funded study suggests
A hormone-releasing intrauterine device (IUD) appears to be as effective at emergency contraception as a copper IUD, suggests a study funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The hormone-releasing IUD contains levonorgestrel, a synthetic form of the reproductive hormone progesterone. Compared to the copper IUD, the levonorgestrel IUD has been shown to reduce heavy bleeding and menstrual discomfort.
Spotlight: Selected NICHD Research Advances of 2020
Read about NICHD’s research findings and activities from 2020.
Spotlight: Selected NICHD Research Advances of 2019
Read about NICHD’s notable research findings and activities from 2019.
Media Advisory: Change in Medicaid reimbursement may reduce rate of closely spaced births among teens
Long-acting contraception after childbirth could help teens avoid short-interval pregnancies, suggests NIH-funded study.
Spotlight: Maternal Health Research Advances
NICHD was established more than 50 years ago to help understand maternal health and improve pregnancy outcomes. These selected advances highlight NICHD’s contributions to advancing the health and well-being of pregnant women, mothers, and families everywhere.
Media Advisory: NICHD chronicles its major research advances of 2018
As 2018 winds down, a new slideshow highlights a selection of initiatives, therapies, and scientific advances supported by NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
Spotlight: Selected NICHD Research Advances of 2018
In 2018, researchers funded by NICHD made significant progress in advancing the health and well-being of infants, children, teenagers, and adults across the United States and around the world.
Release: NIH to evaluate effectiveness of male contraceptive skin gel
A clinical trial funded by the National Institutes of Health will evaluate a male contraceptive gel for its ability to prevent pregnancy.
Spotlight: Selected NICHD Research Advances of 2017
Over the past year, NICHD contributed to numerous scientific advances and key initiatives.
Getting to Know the New NICHD Director
NICHD Director Dr. Diana Bianchi shares some thoughts about joining NICHD.
NICHD appoints new chief for contraception research
NICHD has appointed Daniel S. Johnston, Ph.D., as Chief of its Contraception Research Branch.
Researchers identify molecule needed for sperm activation
Researchers funded by the National Institutes of Health have discovered the cellular switch that boosts the activity of sperm cells so that they can travel to the egg. The finding may lead to new options for male contraception as well as treatments for infertility resulting from problems with sperm mobility.
Obese Young Women Less Likely to Use Birth Control
Obese young women may be less likely to use birth control than their normal-weight peers, placing them at greater risk for unintended pregnancy, according to researchers funded by the National Institutes of Health.