Gynecologic Health and Disease Branch (GHDB)

Under MicroscopeOverview/Mission

GHDB supports basic, translational and clinical research programs related to gynecologic health throughout the reproductive lifespan, beginning at puberty and extending through the early menopause. The branch also supports research training and career development programs for investigators interested in women's reproductive health. Research in the GHDB portfolio may be funded through grants, cooperative agreements, or contracts.

As a newly established branch, efforts focus on sponsoring research in selected gynecologic areas that have either been overlooked or underfunded, including socioeconomic, racial and ethnic disparities in reproductive health outcomes. The branch portfolio includes studies on menstrual disorders, uterine fibroids, endometriosis, ovarian cysts and polycystic ovary syndrome, pelvic floor disorders, as well as studies of the mechanisms underlying chronic pelvic pain, vulvodynia, and dysmenorrhea. Obstetric fistula and female genital cutting are also of interest as they apply to both international and immigrant communities. Emerging emphasis is placed on the role of genomics and epigenomics in elucidating etiology and providing novel approaches for treatment options in an array of gynecologic disorders.

Research directed at gynecologic disorders will provide high quality evidence to direct the development of novel methods for prevention, diagnosis, and treatment of gynecologic disorders with the overall goal of improving women's reproductive health and quality of life.