The mission and vision of the Cell Regulation and Development Group is to increase fundamental knowledge of basic molecular mechanisms of cell biology and animal development and to enhance understanding of how dysregulation of these processes contributes to human disability and disease.
By combining expertise in the genetics of model organisms (including transgenic and null mouse models), cell biology, biochemistry, molecular biology, biophysics, and enzymology, members of the group advance individual research objectives by regularly providing insights and advice to one another and through collaborations enabling synergy in research methods and experimental approaches. These interactions have engendered the development of novel technologies and strategies that will facilitate future discoveries in the areas of molecular mechanisms of synaptic circuit assembly and function, the mechanisms and regulation of protein synthesis and transcriptional activation, the functions and regulation of GRTH/DDX25 in spermatogenesis, the role of signaling pathways in transcriptional control of LH and Prolactin receptors, the identification of molecular markers for diagnosing and treating prostate diseases, technologies based on transposable elements and deep sequencing for genome-wide profiles of gene function, the role of transposable elements in reorganizing the host genome in response to stress, and the mechanisms governing adult organ formation during postembryonic vertebrate development.
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