EB Research: Collaborative Perinatal Project (CPP) Mortality Linkage Study

CPP logoThe overarching goal of this study is investigate the long-term health implications of pregnancy conditions by linking pregnancy data from a large historic pregnancy cohort—the CPP cohort—to the National Death Index (NDI). Ascertaining vital status will allow for the investigation of long-term health associated with pregnancy and neonatal complications.

Linking pregnancy-related health data from women in the CPP with information on cause of death from the NDI represents a significant opportunity to understand health across the life course within a U.S. population. The study will include women who participated in the CPP, a multisite U.S. prospective cohort study from 1959-1965 (n=48,197). Study participant vital status will be assessed through attempted linkage with the NDI utilizing Social Security, state death records, and other sources to augment NDI records, which began in 1979. A successful linkage of such data offers the potential for investigating associations of a wide spectrum of pregnancy-related complications and neonatal outcomes with total mortality and cause-specific mortality.

Principal Investigators

Cuilin Zhang, M.D., M.P.H., Ph.D.

DIPHR Collaborators

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