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Read about NICHD’s research findings and activities from 2021.

Children who were given juice before they were 6 months old drank more juice and soda, and less water, by early and mid-childhood, on average, than children first given juice at or after 12 months, according to a study conducted by researchers at the National Institutes of Health. The findings support a theory that giving children sweet foods and drinks at an early age fosters a preference for sweet tastes that persists into childhood, increasing the risk for childhood weight gain and tooth cavities.

NICHD Director Dr. Diana Bianchi is joined by NIH Office of Research on Women’s Health Director Dr. Janine Clayton in assessing the growing maternal health crisis in the United States and describing NIH’s efforts to address it.

Preliminary data from NICHD-funded researchers provides caregiver-reported information on how children and teens fared during the first months of the COVID-19 pandemic.

For many COVID-19 patients, full recovery remains elusive even long after they should feel “better.” NIH recently announced research opportunities to understand COVID-19 long haulers, who have what researchers now refer to as Post-acute sequelae of SARS-CoV-2 infection (PASC). NICHD joins these opportunities while remaining focused on PASC patients within our audiences of interest—pregnant and lactating people, children, and those with disabilities.

Children in high-poverty neighborhoods who participated in a comprehensive preschool program that provided parents with health and educational services and job training had a lower body mass index in their late 30s than a similar group who participated in the usual early childhood programs, according to a study funded by the National Institutes of Health. The study authors concluded that comprehensive, school-based early childhood programs could lead to improvements in body mass index later in life.

Women with asthma are more likely than normal to gain weight during pregnancy and to retain weight 3 months after giving birth, suggests a National Institutes of Health study. On average, women with asthma gained 3.1 kg (just under 7 lbs) more after a full-term pregnancy than women without asthma. Among women with asthma, weight gain was greater with obesity. Weight gain was also greater with more severe asthma and with asthma triggered by exercise. The study authors suggest that their findings underscore the importance of pre-pregnancy counseling for women with asthma on the need to achieve and maintain a healthy body weight.

National Institutes of Health researchers have discovered a gene in mice that controls the craving for fatty and sugary foods and the desire to exercise. The gene, Prkar2a, is highly expressed in the habenula, a tiny brain region involved in responses to pain, stress, anxiety, sleep and reward. The findings could inform future research to prevent obesity and its accompanying risks for cardiovascular disease and diabetes.

The pandemic reinforces why the NIH INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project matters to families and communities.

NIH has launched a new initiative that will combat the growing problem of maternal mortality and morbidity in the United States.

Negative pressure wound therapy (NPWT) does not appear to lower the risk of infection for obese women after cesarean delivery, suggests a study funded by the National Institutes of Health. The treatment involves placing a low-pressure pump over a closed surgical wound to create negative air pressure. Earlier studies had suggested that NPWT might reduce infection risk and promote healing after surgery. The study of more than 1,600 obese women found no significant difference in infection between women treated with NPWT and those receiving standard wound dressing.

Exercise during pregnancy stimulates fetal production of brown fat, which boosts metabolism and burns calories, even after birth, suggests a mouse study funded by the National Institutes of Health. When fed a high-fat diet, mice born to mothers who exercised had less weight gain than mice whose mothers did not exercise.

Maternal obesity may increase a child’s risk for attention-deficit hyperactivity disorder (ADHD), according to an analysis by NICHD researchers.

Read about NICHD’s notable research findings and activities from 2019.

NICHD’s new initiative—Pregnancy for Every Body—educates plus-size pregnant women about healthy pregnancy and the importance of working with a healthcare provider to develop a pregnancy plan.

Teen girls—but not boys—who prefer to go to bed later are more likely to gain weight, compared to same-age girls who go to bed earlier, suggests a study funded by the National Institutes of Health.

A high genetic risk score for cholesterol and other blood lipids among pregnant women is linked to fetal weight, but varies according to the mother’s racial and ethnic group and obesity status, suggests an analysis by researchers at the Eunice Kennedy Shriver National Institute of Child Health and Human Development.

NIH-supported research calls for well-defined standards for infants between 6 months and 1 year