Researchers funded by the National Institutes of Health have developed an experimental vaccine that reduces stillbirths among rodents born to mothers infected with cytomegalovirus (CMV)--a common virus that can also cause mental retardation and hearing loss in newborn children who were infected in early fetal life.
News
NICHD issues News Releases and Media Advisories to the news media. Spotlight and Research Feature articles explain NICHD research findings and public health issues to the general public. An Item of Interest is a short announcement of relevant information, such as a notable staff change.
Largest-ever Search for Autism Genes Reveals New Clues
The largest search for autism genes to date, funded in part by the National Institutes of Health (NIH), has implicated components of the brain's glutamate chemical messenger system and a previously overlooked site on chromosome 11.
Second Gene Discovered for Recessive Form of Brittle Bone Disease
Researchers at the National Institutes of Health and other institutions have found a second genetic defect that accounts for previously unexplained forms of osteogenesis imperfecta (OI), a disorder that weakens bones, sometimes results in frequent fractures and is sometimes fatal.
Standard Therapy More Effective Than Diabetes Drug for Achieving Pregnancy in Common Fertility Disorder
Metformin, a drug used to treat diabetes and thought to hold great promise at overcoming the infertility associated with polycystic ovary syndrome (PCOS), is less useful for helping women with the condition achieve pregnancy than is the standard treatment with the infertility drug clomiphene, report researchers in an NIH research network.
Hall of Honor Inductee: Dr. Stanley Cohen
When the Institute celebrated the 40th anniversary of its founding in 2003, director Duane Alexander, M.D., initiated the NICHD Hall of Honor as a way to recognize NICHD-supported scientists whose achievements have been especially noteworthy.
Women's Response to Anti-HIV Therapy Improved If Treatment Begins Six Months After Earlier Preventive Regimen
A woman's response to HIV treatment with drug combinations that contain nevirapine is improved if at least six months have passed after she received the drug as a single dose during labor to prevent passing HIV on to her child. (The response to treatment is measured by the reduction of HIV in the blood.)
Gene Discovered for Form of Brittle Bone Disease
Researchers at the National Institutes of Health have discovered that a previously unexplained fatal form of Osteogenesis Imperfecta-a disorder that weakens bones and which may cause frequent fractures-results from a genetic defect in a protein involved in the production of collagen.
Making Malaria History
Malaria—a disease caused by a single-celled parasite—can result in severe headache, high fever, chills, and vomiting. Worldwide, an estimated 300 to 500 million clinical cases of malaria occur each year, and the disease kills more than 1 million children annually.
Malaria Vaccine Prompts Victims' Immune System to Eliminate Parasite From Mosquitoes
Researchers at the National Institutes of Health have developed an experimental vaccine that could, theoretically, eliminate malaria from entire geographic regions, by eradicating the malaria parasite from an area's mosquitoes.
Hormonal Contraception Does Not Appear to Increase HIV Risk
Using hormonal contraception does not appear to increase women's overall risk of infection with the AIDS virus, report the authors of a large study commissioned by the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health.
Brain's Fear Center Shrinks in Autism's Most Severely Socially-Impaired
The brain's fear hub Likely becomes abnormally small in the most severely socially impaired males with autism spectrum disorders, researchers funded by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH) and National Institute on Child Health and Human Development (NICHD) have discovered.
Technology for Monitoring Fetal Oxygen During Labor Offers No Apparent Benefit
A new technology for measuring blood oxygen levels of a baby during labor--expected to provide information useful for preventing birth complications--offers no apparent benefit, report researchers in a National Institutes of Health research network.
World Day for the Prevention of Child Abuse
Abuse of children and adolescents is a complex international problem that seems to defy simple analysis and easy answers. To understand child abuse and exploitation, and to make an impact on the outcomes of these children, the NICHD is joining the American Psychological Association in marking the World Day for Prevention of Child Abuse on November 19.
An Ending and a Beginning: Landmark Research Network Concludes
When autism was first named in 1943 by Dr. Leo Kanner, it was thought to be a rare condition, occurring in fewer than three children in 10,000. By 1996, the estimated incidence of autism was about 12 cases per 10,000 children—not exactly the rate of a rare disorder.
SIDS Infants Show Abnormalities in Brain Area Controlling Breathing, Heart Rate Serotonin-Using Brain Cells Implicated in Abnormalities
Infants who die of sudden infant death syndrome have abnormalities in the brainstem, a part of the brain that helps control heart rate, breathing, blood pressure, temperature and arousal, report researchers funded by the National Institutes of Health.
Backgrounder: Searching for Those at Greatest Risk for SIDS
The current study appears in the November 1 Journal of the American Medical Association provides additional evidence that brainstem abnormalities may impair an infant's ability to sense high carbon dioxide and low oxygen levels.
In Most Comprehensive Study Yet, Two-Week Regimen Helps Stroke Survivors Regain Arm Control
In the largest, most comprehensive study of its kind to date, researchers supported by the National Institutes of Health (NIH) have shown that when stroke survivors who've lost function in one arm are given a unique, two-week rehabilitation regimen that involves restraining their functional arm, they show improvements that last for as long as one year post-treatment.
NIH Opens Health Information Center at Jackson Medical Mall
The National Institutes of Health opened a new health information center today at the Jackson Medical Mall in Jackson, Mississippi, affirming NIH's commitment to providing accurate, up-to-date health information to Mississippi residents.
Gene Linked to Autism in Families with More Than One Affected Child
A version of a gene has been linked to autism in families that have more than one child with the disorder. Inheriting two copies of this version more than doubled a child's risk of developing an autism spectrum disorder, scientists supported by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH) and Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) have discovered.
Drug Prevents PostPartum Hemorrhage in Resource Poor Settings
The drug misoprostol provides a safe, convenient, and inexpensive means to prevent postpartum hemorrhage, a major killer of women in developing countries. The study was conducted by researchers from the University of Missouri, India's Jawaharlal Nehru Medical College, and the National Institutes of Health.