Other Osteogenesis Imperfecta FAQs

Basic information for topics, such as “What is it?” is available in the About Osteogenesis Imperfecta section. Answers to other frequently asked questions (FAQs) specific to osteogenesis imperfecta are in this section.

Can OI lead to cancer?

Studies comparing people with and without OI have found no differences in cancer risks between the two groups.

What if I have OI and want to get pregnant?

OI does not affect fertility. However, about one-half of women with OI give birth by cesarean section. This is because they often have pelvic bone abnormalities that prevent vaginal birth. Women with OI also are more likely to have infants who present in the breech position (feet first).1

Women who have OI, have partners with OI, or have already had a child with OI should consider genetic counseling. A genetic counselor is a healthcare professional who understands the risks of having an infant with OI and can explain prenatal tests that can identify this disorder so that the family can provide care.


  1. Cubert, R., Cheng, E. Y., Mack, S., Pepin, M. G., Byers, P. H. (2001). Osteogenesis imperfecta: Mode of delivery and neonatal outcome. Obstetrics & Gynecology, 97, 66–69.
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