Osteogenesis Imperfecta (OI): Clinical Trials

The NICHD conducts and supports a variety of clinical research related to OI. Select a link below to learn more about these projects.

Featured NICHD Clinical Trials

  • Evaluation and Intervention for the Effects of Osteogenesis Imperfecta
    This is a longitudinal study of the natural history of types III and IV OI in children from birth to 25 years of age. In addition to radiographic, bone density, physical rehabilitation, and dental manifestations of OI, the study will assess the participants’ cardiovascular, pulmonary, neurological, and audiology systems over time.
  • Growth Hormone Therapy in Osteogenesis Imperfecta
    The goals of this trial are to find a cause for the growth plateau common in types III and IV OI, to study the bone’s response to treatment and the effects of treatment, and to find a predictor for response to growth hormone treatment.

NICHD Clinical Trials

ClinicalTrials.gov Search Results

Information on current NIH-sponsored clinical trials on OI is available by following the link below or by calling 800-411-1222.

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