A nurse and a female patient reading a medical booklet together in an examining room.

Who is at risk of amenorrhea?

According to the American Society for Reproductive Medicine, amenorrhea that is not caused by pregnancy, breastfeeding, or menopause occurs in 3% to 4% of women during their lifetime.1 Secondary amenorrhea is more common than primary amenorrhea.

The risk factors for amenorrhea include:2

  • Excessive exercise
  • Obesity
  • Eating disorders, such as anorexia nervosa
  • A family history of amenorrhea or early menopause
  • Genetics, such as having a change to the FMR1 gene, which also causes Fragile X syndrome1


  1. Practice Committee of the American Society for Reproductive Medicine (PC-ASRM). (2008). Current evaluation of amenorrhea. Fertility and Sterility, 90, S219–225. Retrieved May 31, 2016, from http://www.asrm.org/uploadedFiles/ASRM_Content/News_and_Publications/Practice_Guidelines/Educational_Bulletins/Current_evaluation(1).pdf External Web Site Policy (PDF - 146 KB) [top]
  2. Master-Hunter, T., & Heiman, D. L. (2006). Amenorrhea: Evaluation and treatment. American Family Physician, 73, 1374–1382. Retrieved May 31, 2016, from http://www.aafp.org/afp/2006/0415/p1374.html External Web Site Policy [top]

What are the symptoms of amenorrhea?

Who is at risk of amenorrhea?

What causes amenorrhea?

How is amenorrhea diagnosed?

What are the treatments for amenorrhea?


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