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Rett Syndrome: Overview

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Rett syndrome is a neurological and developmental genetic disorder that occurs mostly in females. Infants with Rett syndrome seem to grow and develop normally at first, but then they stop developing and even lose skills in different stages of the disease over a lifetime. The NICHD has supported research on Rett syndrome for the past 25 years and continues to do so in the hope of learning how to slow, stop, and ultimately reverse the disorder's effects.

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Common Names

  • Rett syndrome
  • Rett disorder
  • RTT

Medical or Scientific Names

  • Autism-dementia-ataxia-loss of purposeful hand use syndrome
  • Cerebroatrophic hyperammonemia
Last Updated Date: 04/03/2013
Last Reviewed Date: 01/14/2014