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Pheochromocytoma and Paraganglioma
Pheochromocytomas (often abbreviated as pheos) and paragangliomas (often abbreviated as paras) are rare types of tumors. Pheochromocytomas form in the adrenal glands, while closely related paragangliomas originate from cells of neuronal origin, which can be located throughout the neck, chest, abdomen, or pelvis. These tumors can produce hormones that control the typical body stress reaction and other functions, including heart rate and blood pressure.
NICHD supports and conducts research on pheochromocytoma and paraganglioma to understand the causes of the disease, improve detection methods, and develop effective therapies.
On this webpage, the term “pheochromocytoma” also refers to paraganglioma unless otherwise specified.
General Information
Pheochromocytomas and paragangliomas are rare types of tumors that can make hormones that affect the body’s stress response and other functions, including heart rate and blood pressure.
These tumors cause a variety of symptoms, including headaches, heart palpitations, anxiety, and tremors.
Pheochromocytoma can occur at any age.
About one third of pheochromocytoma cases occur when people inherit a mutated gene from their parents. The remaining two thirds of cases are spontaneous and are not linked to a family history.
A health care provider may use blood and urine tests that measure hormones and their byproducts to diagnose these tumors. The provider may also use imaging or genetic screening.
The cure for a pheochromocytoma is to remove it from the body with surgery. After surgery, there is a chance that the tumor could return.
Treatments are recommended on a case-by-case basis. The most common treatment is surgery.
Research
NICHD conducts and supports research on pheochromocytoma and paraganglioma and on disorders associated with them.
Find a Study
NICHD conducts and supports a variety of clinical research projects related to pheochromocytoma and paraganglioma.
More Information
Find answers to other common questions about pheochromocytoma and paraganglioma, such as whether these tumors can affect pregnancy.
Links to websites of groups that study or provide information about pheochromocytoma and paraganglioma.
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