Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at OPM.gov.

Fragile X-Associated Tremor and Ataxia Syndrome (FXTAS)

FXTAS is a late-onset condition (occurs in people older than age 50) that develops in some men and women with an altered form of the Fragile X gene. Those with FXTAS do not have the intellectual or developmental disabilities common in Fragile X syndrome.

NICHD-supported researchers were the first to identify FXTAS and link it to changes in the FMR1 gene, which causes Fragile X syndrome. The institute is one of several federal agencies working to understand FXTAS and other conditions caused by changes in the FMR1 gene.