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Endometriosis: Clinical Trials

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The NICHD conducts and supports a variety of clinical research related to endometriosis. Select a link below to learn more about these projects.

Featured NICHD clinical trials

  • Bone Marrow Cell Engraftment of the Uterus
    In some women who have had bone marrow transplants, donor tissue has been found in the endometrium. This raises the possibility that it might be possible to use bone marrow cells in therapies for women with disorders of the reproductive system. However, the type of bone marrow cells that grow as endometrial cells in recipients is not yet known. This study’s purpose is to gather endometrial cells from a variety of women to study this phenomenon.
  • Botulinum Toxin for Pelvic Pain in Women With Endometriosis
    Some women with endometriosis have chronic pelvic pain that may be caused by spasms of the pelvic floor muscles, which can be identified by examination. Preliminary studies suggest that botulinum toxin may be able to treat these muscle spasms and reduce the associated pain. This study is testing to see if botulinum toxin injections into the pelvic floor muscles can decrease pain and spasms in women with pelvic pain.
  • Pelvic Pain in Women With Endometriosis
    This study is examining pelvic pain associated with endometriosis and examining better approaches to treatment. Standard treatments-altering hormone levels to prevent endometrial tissue growth or surgically removing endometrial tissue-treat pelvic pain only temporarily. This study is investigating the role of sex hormones, immune chemicals, stress hormones, and genes in pelvic pain and trying to determine how the nerve, muscle, and skeletal systems are involved in this pain.

NICHD Clinical Trials search results

Information on current NIH-sponsored clinical trials is available by following the link below or by calling 800-411-1222.

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