Cushing Syndrome

Cushing syndrome is a condition that occurs when the body is exposed to too much cortisol or a medication similar to cortisol for too long.

Most cases of Cushing syndrome are caused by medications—mainly cortisol-like steroids taken for other conditions, called glucocorticoids. Tumors can also cause Cushing syndrome.

Cushing syndrome causes a range of symptoms. Common ones are weight gain, fatty deposits on the upper back/neck, and skin changes. In children, Cushing syndrome may cause slow rate of growth.

Diagnosing Cushing syndrome can be difficult and often requires several steps that include lab tests and imaging. The syndrome is easier to recognize once it develops fully.

Yes. Many cases of Cushing syndrome are curable. The disease can also be managed with treatments.

Treatments for Cushing syndrome are specific to the cause of the extra cortisol in the body. They can include surgery, stopping cortisol-like steroids, and/or medications.

NICHD conducts and supports research on Cushing syndrome and on conditions related to problems with cortisol.

NICHD conducts and supports a variety of clinical research projects related to Cushing syndrome.

Find answers to other common questions about Cushing syndrome, such as how it affects fertility and pregnancy.

Links to websites of groups that study or provide information about Cushing syndrome.