IDDB sponsors research and research training aimed at preventing and ameliorating intellectual and related developmental disabilities. When the institute was created in 1962, one of its primary charges was to encourage investigations of human development throughout the lifespan, with an emphasis on understanding intellectual and developmental disabilities (IDDs).
The mission of IDDB is to support a program of research in IDDs, including common and rare neuromuscular and neurodevelopmental disorders, such as Down, Fragile X, and Rett syndromes; inborn errors of metabolism; autism spectrum disorders; and conditions currently and soon-to-be detectable through newborn screening. IDDB has a long and respected history of providing support for a diverse portfolio of research projects, contracts, training programs, and research centers dedicated to promoting the well-being of individuals with IDDs at all stages of development.
- Genomic Expert Curation Panels: Pre-application Webinar
For potential applicants for PAR-20-101: Genomic Expert Curation Panels (U24 Clinical Trials No Allowed)
PAR-20-101 Presentation (PDF 2.3 MB)
PAR-20-101 FAQs (PDF 82 KB)
- Fragile X Centers: Pre-application Webinar
For potential applicants for RFA-HD-20-003: Centers for Collaborative Research in Fragile X and FMR1-Associated Conditions (P50 Clinical Trial Optional)
RFA-HD-20-003 Presentation (PDF 529 KB)
RFA-HD-20-003 FAQs (PDF 260 KB)
Informational Pre-Submission Webinar for RFA-HD-20-003: Centers for Collaborative Research in Fragile X and FMR1
- The NICHD-led Trans-NIH Fragile X Coordinating Committee recently published the final NIH Strategic Plan for Research on FMR1-Associated Conditions (PDF 2 MB).
- Down Syndrome Center of Western Pennsylvania Podcast : On the podcast episode "Research at NIH," IDDB Chief Melissa Parisi, M.D., Ph.D., and Lisa Kaeser, J.D., former director of NICHD's Office of Legislation, Public Policy, and Ethics, discuss the DS-Connect® registry and the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) project with Dr. Kishore Vellody, director of the Down Syndrome Center of Western Pennsylvania.