Congenital Anomalies Initiative


The mission of the Congenital Anomalies Initiative (formerly the Birth Defects Initiative) is to capitalize on genomic and other biomedical discoveries to further understanding of the mechanisms responsible for congenital anomalies, which, according to the Centers for Disease Control and Prevention, affect about 3% of all live births in the United States each year.

The goal is the development of new, innovative, and valuable strategies for the molecular diagnosis, treatment, and prevention of human structural congenital anomalies. It is led by the Developmental Biology and Congenital Anomalies Branch (DBCAB), formerly known as the Developmental Biology and Structural Variation Branch.

Through the initiative, DBCAB supports basic scientists and clinicians whose research projects span basic, translational, and clinical approaches to understanding the developmental biology and genetics of structural congenital anomalies.

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