Formed in 1986, the NICHD Neonatal Research Network (NRN) is a collaborative network of neonatal intensive care units across the United States. The NRN comprises 18 clinical centers and a data coordinating center. Focused on newborns, particularly extremely low birth weight (ELBW) infants, the NRN aims “to facilitate the advancement of neonatal care by establishing a network of academic centers that, by rigorous patient evaluation using common protocols, can study the required numbers of patients and can provide answers more rapidly than individual centers acting alone (RFA HD10-003).” To fulfill this mission, the NRN has completed or is implementing 18 observational studies and 34 interventional trials (details of which are available at www.clinicaltrials.gov and on the NRN website at neonatal.rti.org ). As of August 2013 , ongoing clinical trials and observational studies focus on several topic areas that are discussed below.
Over its 27-year history, the Neonatal Research Network has published more than 275 peer-reviewed papers. Presented below are some high-impact results from NRN studies. A complete listing of NRN studies and papers is available on the NRN website .
Current clinical sites within the NRN include:
Collaborating clinical sites (collecting follow-up data on recruited subjects) include:
RTI International serves as the Data Coordinating Center for the NRN.