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The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at OPM.gov.

Publications

  • A multiplex CRISPR interference tool for virulence gene interrogation in Legionella pneumophila. Ellis NA, Kim B, Tung J, Machner MP. 2021. Commun Biol. 4(1):157.
  • The Legionella kinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation. Lee PC, Beyrakhova K, Xu C, Boniecki MT, Lee MH, Onu CJ, Grishin AM, Machner MP, Cygler M. 2020. PNAS 117(25):14433-14443.
  • The Legionella Effector Kinase LegK7 Hijacks the Host Hippo Pathway to Promote Infection. Lee PC, Machner MP. 2018. Cell Host & Microbe 24:429-438.
  • VipD is a Rab5-activated phospholipase A1 that protects Legionella pneumophila from endosomal fusion. Gaspar AH and Machner MP. 2014. PNAS  111(12):4560-5
  • De-AMPylation of the small GTPase Rab1 by the pathogen Legionella pneumophila. Neunuebel MR, Chen Y, Gaspar AH, Backlund Jr. PS, Yergey A, Machner MP. 2011. Science  333:453-456.

A complete listing of Dr Machner's publications can be found by visiting My NCBI Collections.

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