If we knew what it was we were doing, it would not be called research, would it?
- Albert Einstein

Current Projects:

Extracellular Matrix Disorders: Molecular Mechanisms and Treatment Targets

  • Regulation of collagen synthesis, quality control, trafficking, and degradation in fibroblasts and osteoblasts 
  • Osteogenesis Imperfecta: cell culture and mouse models, molecular mechanisms, treatment targets, and development of novel treatments
  • Translational and mechanistic studies of collagen and proteoglycan related pathology in other forms of skeletal dysplasia, fibrosis, and cancer 

High-definition micro-spectroscopic imaging and analysis of biomaterials

  • Development of high-definition micro-spectroscopic imaging technology
  • Real-time, label-free imaging of biochemical reactions in tissue sections and live cell cultures
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