(*co-corresponding authors)

• Qiu H, Chereji RV, Hu C, Cole HA, Rawal Y, Clark DJ*, Hinnebusch AG*. Genome-wide cooperation by HAT Gcn5, remodeler SWI/SNF, and chaperone Ydj1 in promoter nucleosome eviction and transcriptional activation. Genome Res. 26:211-25, 2016.
• Sen ND, Zhou F, Harris MS, Ingolia NT, Hinnebusch AG. eIF4B stimulates translation of long mRNAs with structured 5' UTRs and low closed-loop potential but weak dependence on eIF4G. Proc Natl Acad Sci USA 113: 10464-10472, 2016.
• Aitken CE, Beznosková P, Vlckova V, Chiu WL, Zhou F, Valášek LS*, Hinnebusch AG*, Lorsch JR*. Eukaryotic translation initiation factor 3 plays distinct roles at the mRNA entry and exit channels of the ribosomal preinitiation complex. Elife. 5: e20934, 2016.
• Visweswaraiah J, Hinnebusch AG. Interface between 40S exit channel protein uS7/Rps5 and eIF2α modulates start codon recognition in vivo. Elife. 6: e22572, 2016.
• Hinnebusch AG, Ivanov IP, Sonenberg N. Translational control by 5'-untranslated regions of eukaryotic mRNAs. Science. 352:1413-6, 2016.
• Dong J, Aitken CE, Thakur A, Shin BS, Lorsch JR*, Hinnebusch AG*. Rps3/uS3 promotes mRNA binding at the 40S ribosome entry channel and stabilizes preinitiation complexes at start codons. Proc Natl Acad Sci USA 114:E2126-E2135, 2017.
• Obayashi E, Luna RE, Nagata T, Martin-Marcos P, Hiraishi H, Singh CR, Erzberger JP, Zhang F, Arthanari H, Morris J, Pellarin R, Moore C, Harmon I, Papadopoulos E, Yoshida H, Nasr ML, Unzai S, Thompson B, Aube E, Hustak S, Stengel F, Dagraca E, Ananbandam A, Gao P, Urano T, Hinnebusch AG, Wagner G, Asano K. Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5. Cell Rep. 18:2651-2663, 2017.
• Yourik P, Aitken CE, Zhou F, Gupta N, Hinnebusch AG*, Lorsch JR*. Yeast eIF4A enhances recruitment of mRNAs regardless of their structural complexity. Elife. 6: e31476, 2017.
• Martin-Marcos P, Zhou F, Karunasiri C, Zhang F, Dong J, Nanda J, Kulkarni SD, Sen ND, Tamame M, Zeschnigk M, Lorsch JR*, Hinnebusch AG*. eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast. Elife. 6: e31250, 2017.
• Hinnebusch AG. Structural Insights into the Mechanism of Scanning and Start Codon Recognition in Eukaryotic Translation Initiation. Trends Biochem Sci. 42:589-611, 2017.
• Rawal Y, Chereji RV, Valabhoju V, Qiu H, Ocampo J, Clark DJ*, Hinnebusch AG*. Gcn4 Binding in Coding Regions Can Activate Internal and Canonical 5' Promoters in Yeast. Mol Cell. 70(2):297-311.e4, 2018.
• Thakur A, Hinnebusch AG. eIF1 Loop 2 interactions with Met-tRNAi control the accuracy of start codon selection by the scanning preinitiation complex. Proc Natl Acad Sci USA. 115:E4159-E4168, 2018.
• Rawal Y, Chereji RV, Qiu H, Ananthakrishnan S, Govind CK*, Clark DJ*, Hinnebusch AG*. SWI/SNF and RSC cooperate to reposition and evict promoter nucleosomes at highly expressed genes in yeast. Genes Dev. 32:695-710, 2018.
• Young DJ, Makeeva DS, Zhang F, Anisimova AS, Stolboushkina EA, Ghobakhlou F, Shatsky IN, Dmitriev SE*, Hinnebusch AG*, Guydosh NR*. Tma64/eIF2D, Tma20/MCT-1, and Tma22/DENR Recycle Post-termination 40S Subunits In Vivo. Mol Cell. 71:761-774, 2018.
• Gupta N, Lorsch JR*, Hinnebusch AG*. Yeast Ded1 promotes 48S translation pre-initiation complex assembly in an mRNA-specific and eIF4F-dependent manner. Elife. Oct 3;7, pii: e38892, 2018.
• Gunišová S, Hronová V, Mohammad MP, Hinnebusch AG, Valášek LS. Please do not recycle! Translation reinitiation in microbes and higher eukaryotes. FEMS Microbiol Rev. 42:165-192, 2018.
• Llácer JL, Hussain T, Saini AK, Nanda JS, Kaur S, Gordiyenko Y, Kumar R, Hinnebusch AG*, Lorsch JR*, Ramakrishnan V*. Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition. Elife. 2018 Nov 30;7. pii: e39273.
• Zeidan Q, He F, Zhang F, Zhang H, Jacobson A, Hinnebusch AG. Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo. PLoS Genet. 2018 Dec 7;14(12):e1007806.
• Thakur A, Marler L, Hinnebusch AG. A network of eIF2β interactions with eIF1 and Met-tRNAi promotes accurate start codon selection by the translation preinitiation complex. Nucleic Acids Res. 2019 47(5):2574-2593.
• Sen ND, Gupta N, K Archer S, Preiss T, Lorsch JR, Hinnebusch AG. Functional interplay between DEAD-box RNA helicases Ded1 and Dbp1 in preinitiation complex attachment and scanning on structured mRNAs in vivo. Nucleic Acids Res. 2019. pii: gkz595. doi: 10.1093/nar/gkz595 [Epub ahead of print].