Publications

2021

  • A.M. Berezhkovskii, and S.M. Bezrukov.  Capturing single molecules by nanopores: Measured times and thermodynamics. Physical Chemistry Chemical Physics, 2021, 23:1610–1615.
  • D.P. Hoogerheide, T.K. Rostovtseva, D. Jacobs, P.A. Gurnev, and S.M. Bezrukov.  Tunable electromechanical nanopore trap reveals populations of peripheral membrane protein binding conformations. ACS Nano, 2021, 15:989–1001.
  • A.T. Skvortsov, L. Dagdug, A.M. Berezhkovskii, I.R. MacGillivray, and S.M. Bezrukov.  Evaluating diffusion resistance of a constriction in a membrane channel by the method of boundary homogenization. Physical Review E, 2021, 103:012408.
  • L. Dagdug, A.M. Berezhkovskii, V.Yu. Zitserman, and S.M. Bezrukov. Trapping of particles diffusing in two dimensions by a hidden binding site. Physical Review E, 2021, 103:012135.
  • W.M. Rosencrans, M. Rajendran, S.M. Bezrukov, and T.K. Rostovtseva. VDAC regulation of mitochondrial calcium flux: From channel biophysics to disease. Cell Calcium, 2021, 94:102356.
  • W.M. Rosencrans, V.M. Aguilella, T.K. Rostovtseva, and S.M. Bezrukov. α-Synuclein emerges as a potent regulator of VDAC-facilitated calcium transport. Cell Calcium, 2021, 95:102355.
  • A.M. Berezhkovskii, S.M. Bezrukov, and D.E. Makarov. Localized potential well vs. binding site: Mapping solute dynamics in a membrane channel onto one-dimensional description. Journal of Chemical Physics, 2021, 154:111101.

2020

  • A. Rovini, P.A. Gurnev, A. Beilina, M. Queralt-Martín, W. Rosencrans, M.R. Cookson, S.M. Bezrukov, and T.K. Rostovtseva.  Molecular mechanism of olesoxime-mediated neuroprotection through targeting α-synuclein interaction with mitochondrial VDAC. Cellular and Molecular Life Sciences, 2020, 77:3611–3626.
  • A.M. Berezhkovskii, L. Dagdug, and S.M. Bezrukov.  Peculiarities of the mean transition path time dependence on the barrier height in entropy potentials. Journal of Physical Chemistry B, 2020, 124:2305−2310.
  • T.K. Rostovtseva, M. Queralt-Martín, W.M. Rosencrans, and S.M Bezrukov.  Targeting the multiple physiologic roles of VDAC with steroids and hydrophobic drugs. Frontiers Physiology, 2020, 11:446.
  • D.P. Hoogerheide, P.A. Gurnev, T.K. Rostovtseva, and S.M. Bezrukov.  Effect of a post-translational modification mimic on protein translocation through a nanopore. Nanoscale, 2020, 12:11070–11078.
  • M. Queralt-Martín, D. P. Hoogerheide, S. Yu. Noskov, A. M. Berezhkovskii, T. K. Rostovtseva, and S. M. Bezrukov.  VDAC gating thermodynamics, but not gating kinetics, are virtually temperature independent. Biophysical Journal, 2020, 119:2584–2592.

2019

  • M. Queralt-Martín, L. Bergdoll, D. Jacobs, S.M. Bezrukov, J. Abramson, and T.K. Rostovtseva.  Assessing the role of residue E73 and lipid headgroup charge in VDAC1 voltage gating. Biochimica et Biophysica Acta – Bioenergetics, 2019, 1860:22–29.
  • A.M. Berezhkovskii, L. Dagdug, and S.M. Bezrukov.  Trapping of diffusing particles by small absorbers localized in a spherical region. Journal of Chemical Physics, 2019, 150:064107.
  • D. Jacobs, D.P. Hoogerheide, A. Rovini, Z. Jiang, J.C. Lee, T.K. Rostovtseva, and S.M. Bezrukov. Probing membrane association of alpha-synuclein domains with VDAC nanopore reveals unexpected binding pattern. Scientific Reports, 2019, 9:4580.
  • A.M. Berezhkovskii, L. Dagdug, and S.M. Bezrukov.  Exact solutions for distributions of first-passage, direct-transit, and looping times in symmetric cusp potential barriers and wells.  Journal of Physical Chemistry B, 2019, 123:3786–3796.
  • A.M. Berezhkovskii and S.M. Bezrukov.  Blocker escape kinetics from a membrane channel analyzed by mapping its diffusive dynamics onto a two-site model. Journal of Chemical Physics, 2019, 150:194103.
  • A.M. Berezhkovskii, L. Dagdug, and S.M. Bezrukov.  Two-site versus continuum diffusion model of blocker dynamics in a membrane channel: Comparative analysis of escape kinetics.  Journal of Chemical Physics, 2019, 151:054113.
  • M. Queralt-Martín, L. Bergdoll, O. Teijido, N. Munshi, D. Jacobs, A.J. Kuszak, O. Protchenko, S. Reina, A. Magrì, V. De Pinto, S.M. Bezrukov, J. Abramson, and T.K. Rostovtseva.  A lower affinity to cytosolic proteins reveals VDAC3 isoform-specific role in mitochondrial biology. Journal of General Physiology, 2019, e201912501.

2018

  • D.P. Hoogerheide, P.A. Gurnev, T.K. Rostovtseva, and S.M. Bezrukov.  Real-time nanopore-based recognition of protein translocation success.  Biophysical Journal, 2018, 114:772–776.
  • A.M. Berezhkovskii and S.M. Bezrukov. Stochastic gating as a novel mechanism for channel selectivity. Biophysical Journal, 2018, 114:1026–1029.
  • A.M. Berezhkovskii and S.M. Bezrukov. Effect of stochastic gating on the flux through a membrane channel: A steady-state approach. Journal of Physics: Condensed Matter, 2018, 30:254006.
  • T.K. Rostovtseva, P.A. Gurnev, D.P. Hoogerheide, A. Rovini, M. Sirajuddin, and S.M. Bezrukov. Sequence diversity of tubulin isotypes in regulation of the mitochondrial voltage-dependent anion channel. Journal of Biological Chemistry, 2018, 293:10949 –10962.
  • A.M. Berezhkovskii and S.M. Bezrukov. Mapping intra-channel diffusive dynamics of interacting molecules onto a two-site model: Crossover in flux concentration dependence. Journal of Physical Chemistry B, 2018, 122:10996−11001.

2017

BOOK CHAPTER:

2016

2015

BOOK CHAPTERS:

2014

2013

2012

2011

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