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Updates regarding government operating status and resumption of normal operations can be found at OPM.gov.

What are the symptoms of neural tube defects?

The symptoms associated with NTDs vary depending on the specific type of defect. 

Symptoms include physical problems (such as paralysis and urinary and bowel control problems), blindness, deafness, intellectual disability, lack of consciousness, and, in some cases, death. Some people with NTDs have no symptoms. Most children with certain types of NTDs die or experience serious disability.