Active Funding Opportunities and Notices for NICHD

NICHD publishes and participates in various notices of funding opportunities (NOFOs) and NIH Guide Notices (NOTs) to support research and training activities.

NOTs and Active NOFOs for NICHD

Please note: the following are sorted by date, from most recent to older. Select a table heading to change how to sort the information.

Number Exp. Date Activity Code(s) Title Sort ascending
PAR-23-309 November 6, 2026 R01 Health and Health Care Disparities Among Persons Living with Disabilities (R01 - Clinical Trials Optional)
RFA-NS-24-021 February 7, 2025 R01 HEAL Initiative: Understanding Individual Differences in Human Pain Conditions (R01 - Clinical Trial Optional)
RFA-EB-22-002 June 18, 2025 R18 HEAL Initiative: Translational Development of Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)
RFA-NS-25-012 January 16, 2027 R61/R33 HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
NOT-NS-19-014 January 1, 2027 HEAL Initiative: Notice of Interest in Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Applications Directed at Enhanced Pain Management and Improved Treatments for Opioid Misuse and Addiction
RFA-NS-24-019 January 8, 2027 UG3/UH3 HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
RFA-NS-23-003 June 10, 2025 RM1 HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional)
RFA-NS-23-028 June 10, 2025 RM1 HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional)
RFA-NS-22-034 December 7, 2024 R01 HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)
RFA-NS-23-006 April 5, 2025 R43/R44 HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)
RFA-NS-23-007 April 5, 2025 R41/R42 HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)
PAR-24-197 July 17, 2026 R03 HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)
NOT-NS-22-095 June 25, 2025 R61/R33 HEAL Initiative Notice of Special Interest (NOSI): Development and Validation of Pain-Related Models and Endpoints to Facilitate Non-Addictive Analgesic Discovery
RFA-NS-22-025 March 12, 2025 K99/R00 HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed)
RFA-NS-22-024 March 12, 2025 K99/R00 HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research to Promote Diversity (K99/R00 Independent Basic Experimental Studies with Humans Required)
RFA-NS-22-022 March 12, 2025 K99/R00 HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research (K99/R00 Independent Clinical Trial Not Allowed)
RFA-NS-22-023 March 12, 2025 K99/R00 HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research (Independent Basic Experimental Studies with Humans Required)
PAR-22-098 December 10, 2024 R21 Global Brain and Nervous System Disorders Research Across the Lifespan (R21 Clinical Trial Optional)
PAR-22-097 December 10, 2024 R01 Global Brain and Nervous System Disorders Research Across the Lifespan (R01 Clinical Trials Optional)
NOT-OD-12-019 January 1, 2027 Frequently Asked Questions for RFA-MH-12-130 - OppNet's Basic Research on Decision Making: Cognitive, Affective, and Developmental Perspectives (R01)
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