Pharmacokinetic Studies of Life-Saving Drugs in Children Receiving Continuous Renal Replacement Therapy: Necessity, Experience, & Opportunity

May 14, 2015, at 11:00 a.m. EDT (Webinar)


Obstetric and Pediatric Pharmacology and Therapeutics Branch (OPPTB), Division of Extramural Research (DER), NICHD


The Russell Chesney Memorial Lecture in Pediatric Nephrology Webinar is held in honor of the late Dr. Russell Chesney, one of the founding investigators of the NICHD-funded Pediatric Pharmacology Research Unit Network, but also a respected scientist, clinician, teacher, mentor, and leader in pediatric nephrology.

During this webinar, Dr. Stuart Goldstein External Web Site Policy, of the Cincinnati Children’s Hospital Medical Center, will discuss the issues that prevent optimal dosing of life-saving medications in critically ill patients with acute kidney injury (AKI) who receive continuous renal replacement therapy (CRRT). Current research initiatives aimed at improving our ability to optimally dose these medications, including an academic partnership with U.S. Food and Drug Administration (FDA) will also be discussed.

Objectives for the webinar include the following:

  • Describe the outcomes of critically ill patients with AKI who receive CRRT
  • Describe the state of the art in CRRT pharmacokinetics
  • Discuss current CRRT pharmacokinetic initiatives in the children, including the Pediatric Trials Network efforts and the Kidney Health Initiative, which is a collaboration between the American Society of Nephrology and the FDA.

This lecture is also part of the NICHD’s Sumner J. Yaffe Memorial Lecture Series External Web Site Policy.


Dr. George Giacoia, OPPTB, DER, NICHD
Tel: (301) 496–5589

Please note: Views expressed during NICHD-sponsored events do not necessarily reflect the opinions or the official positions of NICHD, NIH, or HHS.
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