Program seeks Council approval for an initiative titled "NICHD International and Domestic Pediatric and Maternal HIV Studies Coordinating Center". The NICHD Maternal and Pediatric Infectious Disease Branch (MPIDB) develops, implements and directs a wide range of domestic and international research activities for the study of the pathogenesis, epidemiology, risk factors and co-factors for HIV and related co-infections in pregnant women, infants, children, and adolescents. The evaluation of new and improved therapies for treatment of HIV infection and its associated complications in children and pregnant women and further reduction of perinatal transmission is a high priority for the NICHD. The goal of this initiative is the evaluation of new and improved therapies for treatment of HIV infection and its associated complications in children and pregnant women and further reduction of perinatal transmission. Unique aspects of HIV infection in children and pregnant women require a pediatric/perinatal-specific clinical trials system that includes sites with the enrollment capacity to expediently evaluate therapeutic agents in HIV-infected infants, children and pregnant women. This initiative will continue providing support for critical infrastructure to enhance maternal, pediatric, and adolescent HIV therapeutic and prevention research, including vaccine and HIV cure research activities on a global scale.
This proposed initiative aligns with the NICHD vision of Behavior and Environment.
This proposed initiative is also conceptually in alignment with five of the eight Office of AIDS Research High priority topics. These topics include the development of next generation HIV therapies with better safety and ease to use, research toward cure and research to reduce the incidence of HIV/AIDS developing and testing vaccines, microbicides and pre-exposure prophylaxis.
Maternal and Pediatric Infectious Disease Branch
Back to Concept Review by Council