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Pregnant people need to be protected through research rather than from research, the authors contend.

As the COVID-19 pandemic persists, SARS-CoV-2 vaccines offer the potential to halt the spread of the virus. Yet, we know very little about the effectiveness and safety of the vaccines during pregnancy.

NIH-funded study suggests mother-to-infant transmission appears to be rare

Increased stress may interfere with adjustment to new motherhood, mother-infant bonding

Read about NICHD’s research findings and activities from 2020.

Very low birthweight infants often need blood transfusions to survive. A National Institutes of Health-funded study suggests that providing a higher threshold of red cells within accepted limits offers no advantage in survival or reduction in neurological impairment over a lower threshold.

Pregnant women who are infected with SARS-CoV-2, the virus that causes COVID-19, during the third trimester are unlikely to pass the infection to their newborns, suggests an NIH-funded study.

Vegetarian diets during pregnancy are associated with small infant birth weight, but not a higher risk preterm birth or other medical complications, suggests a National Institutes of Health study.

National Institutes of Health study suggests women with mood disorders, gestatational diabetes may have a higher risk.

Researchers funded by the National Institutes of Health have used a rapid DNA sequencing technique to identify gene variants in roughly a third of cases of nonimmune Hydrops fetalis (NIHF), a serious condition in which a fetus develops fluid buildup inside the abdominal cavity, lungs, or other parts of the body. The findings suggest that the DNA sequencing technique, known as exome sequencing, could be used to provide information unavailable with current genetic testing methods.

The study of approximately 16,000 pregnant women will continue 12 months after childbirth and compare maternal, fetal and newborn outcomes of participants infected with the virus to those of pregnant women who have not.

Compared to other women, deaf and hard of hearing women have a higher risk for pregnancy and birth complications such as gestational diabetes and blood pressure disorders, according to a study funded by NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development. Moreover, infants of deaf and hard of hearing women were more likely to be born preterm, have low birth weight, and receive a low Apgar score—a screening test used to determine the baby’s need for additional medical services.

Researchers to evaluate medical records of 21,000 pregnant women

Program will include lessons learned from caring for pregnant women with COVID-19.

The earlier in pregnancy infants were born, the more likely they were to fail a screening test for developmental delay by age 3, according to a study by researchers at the National Institutes of Health and other institutions. Although infants born at 39 weeks, considered full term, had a lower risk than those born earlier, infants born at 40 and 41 weeks had even lower risks. The findings may have implications for elective induction—labor induced when there is no medical need—at 39 weeks.

Drug labels for doxycycline, clindamycin and caffeine citrate now include better information for healthcare providers on recommended usage and dosage in pediatric populations.

Researchers at the National Institutes of Health have discovered in mice what they believe is the first known genetic mutation to improve cognitive flexibility—the ability to adapt to changing situations.

Researchers have developed a test to measure the expressive language skills of people with Fragile X syndrome, a genetic disorder that may result in intellectual disability, cognitive impairment and symptoms of autism spectrum disorder. Expressive language refers to the use of words to convey meaning to others. The work was funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, part of the National Institutes of Health.

A research team funded by the National Institutes of Health has updated an online tool to provide information for clinicians and parents on outcomes for extremely preterm infants. The key change in the update was the incorporation of data from the hospital where the infant was born, which the researchers found was as important as gestational age in determining infant outcome.

To expand the reach of its crowdsourcing pregnancy research project, the National Institutes of Health (NIH) recently launched a Spanish version of PregSource®.