News

Infertility treatments with ovulation drugs or intrauterine insemination—in which sperm is placed directly into the uterus—are associated with a higher likelihood of preterm birth, suggests a study funded by the National Institutes of Health.

Hydrocortisone is no more effective than placebo at preventing damage that can result from oxygen and ventilator therapy necessary to keep preterm infants alive, according to research funded by the National Institutes of Health. The study of a potential treatment for the condition, known as bronchopulmonary dysplasia, appears in the New England Journal of Medicine.

Life-threatening pregnancy complications known as severe maternal morbidity (SMM) appear to be associated with an increased length of hospital stay for infants and an increase in the cost of caring for them, suggests a study funded by the National Institutes of Health. The findings support the hypothesis that infants of mothers with SMM may also be at risk for severe complications. The authors concluded that helping patients to reduce their risk factors—in early pregnancy or before conception—may reduce the chances for SMM and improve the health of infants.

How early can a baby be born and not only survive but thrive? Dr. Bianchi discusses continued progress in saving extremely preterm infants and highlights NICHD’s efforts to prevent preterm births and improve the care of premature babies.

Taking supplemental docosahexaenoic acid (DHA) during pregnancy may decrease the risk of preterm birth. A new NICHD-supported study offers a potential explanation for this effect by suggesting that a daily 1,000-milligram dose of DHA influences certain inflammatory immune responses linked to childbirth.

The survival rate of extremely preterm infants born from 2013 through 2018 in a large network of U.S. research centers improved to 78.3%, compared to 76% for infants born in the network from 2008 to 2012, according to researchers funded by the National Institutes of Health.

An individual’s risk for death by suicide may begin before they are born, suggests a study by researchers at the National Institutes of Health. The authors compared pregnancy and birth records of nearly 50,000 individuals born between 1959 and 1966 to death records through 2016. They found that suicide rates were higher for males, white people, and for those who were among the younger siblings in a family. Other risk factors included having a parent with less than a high school education, having a parent who worked a manual labor job, and having a mother with a high rate of pregnancy complications or who smoked during pregnancy.

Read about NICHD’s research findings and activities from 2021.

It just got easier to participate in the PregSource®: Crowdsourcing to Understand Pregnancy research project. The free app allows participants to track their weight, sleep, mood, and other features of their pregnancy in just a few taps.

Dr. Grewal has been acting director of the division since February 2020.

Among 6- and 7-year-olds who were born extremely preterm—before the 28th week of pregnancy—those who had more than two hours of screen time a day were more likely to have deficits in overall IQ, executive functioning (problem solving skills), impulse control and attention, according to a study funded by the National Institutes of Health.

The National Institutes of Health will award up to $400,000 to individuals or groups who design an effective method for analyzing a large data set of first-time pregnancies and identifying risk factors for adverse outcomes, such as hypertensive disorders, diabetes and infection. A total of $50,000 will be awarded to each of seven winners designing the most effective means to analyze the data. An additional $10,000 will be awarded to the top five winners whose methods identify risk factors in disadvantaged populations.

An analysis funded by the National Institutes of Health confirmed the safety of daily low-dose aspirin to prevent preterm birth in first-time mothers with a singleton pregnancy in low- and middle-income countries. Compared to the placebo group, those in the aspirin group were no more likely to require an unexpected emergency medical visit or to experience any side effects, other than a mild skin rash.

Researchers at the National Institutes of Health have developed a prototype device that could potentially diagnose pregnancy complications by monitoring the oxygen level of the placenta.

Women in the first trimester of pregnancy when President John F. Kennedy was assassinated in 1963 were more likely to deliver preterm compared to women who gave birth before the assassination, according to an analysis by NIH-funded researchers. The findings suggest that experiencing a sudden stress early in pregnancy may increase the risk of adverse birth outcomes.

A healthy diet around the time of conception through the second trimester may reduce the risk of several common pregnancy complications, suggests a study by researchers at the National Institutes of Health.

Women assigned to 1,000 mg of an omega-3 fatty acid, docosahexaenoic acid (DHA), daily in the last half of pregnancy had a lower rate of early preterm birth (<34 weeks gestation) than women who took the standard dose of 200 mg, found in many prenatal supplements, according to a study funded by the National Institutes of Health. Women who entered the study with low baseline DHA levels had the greatest reduction in early preterm birth.

NICHD Director Dr. Diana Bianchi is joined by NIH Office of Research on Women’s Health Director Dr. Janine Clayton in assessing the growing maternal health crisis in the United States and describing NIH’s efforts to address it.

A team of researchers funded by the National Institutes of Health has developed a new ultrasound technique to monitor the placenta for impaired fetal blood flow early in pregnancy. The technique, which uses conventional ultrasound equipment, relies on subtle differences in the pulsation of fetal blood through the arteries at the fetal and placental ends of the umbilical cord, potentially enabling physicians to identify placental abnormalities that impair fetal blood flow and, if necessary, deliver the fetus early.

Women facing eviction from their homes while they were pregnant are more likely to have poor birth outcomes, compared to women who faced eviction before or after they were pregnant, according to a study funded in part by NICHD.