An AI program has the potential to identify signs of childbirth related post-traumatic stress disorder by evaluating short narratives of patients who have given birth. With further refinements, the program could potentially identify a large proportion of those at risk.
News
NICHD issues News Releases and Media Advisories to the news media. Spotlight and Research Feature articles explain NICHD research findings and public health issues to the general public. An Item of Interest is a short announcement of relevant information, such as a notable staff change.
Item of Interest: NIH-funded report recommends strategies to advance inclusion of pregnant and lactating women in clinical research
A report issued by the National Academies of Science, Engineering, and Medicine makes recommendations to improve the safe and ethical inclusion of pregnant and lactating women in clinical research while reducing the risk of liability. Enhancing inclusion of pregnant and lactating people in clinical research promises to help people and their health care providers make informed decisions.
Director's Corner: Addressing Infertility
Infertility affects millions of lives. NICHD supports research to better understand its causes and contributing factors and to improve treatments for both male and female inferility.
Science Update: Preterm infant hernia surgery safer after initial hospital discharge, NIH-funded study suggests
Infants who underwent surgery for inguinal hernia—when intestinal tissue protrudes through an abnormal opening in the abdominal muscles—after discharge had fewer adverse events than those who had surgery while still in the hospital, a study suggests. The findings offer guidance on the best timing to perform this delicate surgery on fragile infants.
Media Advisory: Irregular sleep and late bedtimes associated with worse grades for high school students
Irregular sleep and late bedtimes are linked to worse grades and more school-related behavioral problems among teens, a new study suggests. Interventions to promote regular sleep hours could potentially boost their academic performance.
Science Update: Stress, microRNA linked to uterine fibroids, preliminary NIH-funded study suggests
Patients with uterine fibroids who scored high on stress questionnaires also had high levels of certain microRNAs—which regulate genes--in their uterine muscle tissue. The findings add to previous studies linking stress to the development and severity of fibroids.
Science Update: Relatives of men with infertility may be at higher risk for certain cancers, NIH-funded study suggests
Relatives of men with no or a very low sperm count may be at higher risk for cancers. The findings may lead to new ways for identifying people at risk.
Media Advisory: Repurposed drug shows promise against endometriosis-related pain in animal model
An NIH-funded study suggests that fenoprofen may be a potential therapeutic for endometriosis, a disease that affects approximately 1 in 10 U.S. women. The researchers used a computer algorithm to evaluate nearly 1,300 existing drugs and tested their top candidate, fenoprofen, in a rodent model of the disease.
Item of Interest: NIH-funded research leads to fluconazole labeling updates for use in infants
Health care providers often use the antifungal drug fluconazole “off-label” to prevent and treat fungal infections in infants. Thanks to NICHD-funded research, fluconazole labels now include information about the drug’s recommended usage and dosage in infants, including those born prematurely.
Director's Corner: Elucidating the Effects of Digital Media on Children
NICHD has a longstanding commitment to research on the effects of exposure to and use of technology and digital media from infancy through adolescence. Since 2020, the Institute has expanded its research in this area to advance toward the goal of discovering how such exposure and use affect developmental trajectories, health outcomes, and parent-child interactions in early childhood.
Spotlight: NIH Panel Explores Endometriosis Advances, Emphasizes Awareness
Around 200 million people worldwide live with endometriosis, a common gynecological disease with symptoms that include pelvic pain, fatigue, and infertility. NICHD recently hosted a discussion about advances and new directions in endometriosis research, and the imperative of raising awareness and education about the disease.
Release: Children Surpass a Year of HIV Remission after Treatment Pause
Four children enrolled in an NIH-funded study have remained free of detectable HIV for more than one year after their antiretroviral therapy was paused to see if they could achieve HIV remission, researchers report. The findings suggest that very early HIV treatment enables unique features of the neonatal immune system to limit HIV reservoir development, increasing the prospect of HIV remission.
Item of Interest: NIH awards interim prizes in fetal diagnostic and monitoring technology competition
NIH has announced finalists in its competition to accelerate the development of diagnostic and monitoring
technologies to improve fetal health outcomes.
Science Update: Placental particles in maternal bloodstream may signal less fetal growth, NIH-funded study suggests
Tiny, balloon-like particles released from the placenta could provide clues to identify fetuses at risk for growth restriction early so that pregnancies could be monitored for complications.
Science Update: Timing of COVID-19 vaccination drives menstrual cycle changes, NIH-funded study suggests
People who receive a COVID-19 vaccine during the first half of the menstrual cycle are more likely to experience a small, temporary increase in cycle length than those vaccinated during the second half, suggests an NICHD-funded study. By providing additional information about what to expect after a COVID-19 vaccine, the findings may help ease fears and anxiety around vaccination.
Science Update: Omega-3 supplements may reduce schizotypal personality symptoms, NIH-funded study suggests
Taking an omega-3 fatty acid supplement lowered children’s scores for schizotypal personality disorder, which features unusual thoughts, speech, and behaviors that hinder the ability to form relationships. The results suggest that regular supplementation in childhood could prevent more severe symptoms from developing in adolescence.
Director's Corner: Preventing Sexually Transmitted Infections
There were more than 2.5 million cases of syphilis, gonorrhea, and chlamydia in the United States in 2022. NICHD research aims to prevent these and other sexually transmitted infections (STIs) among women, infants, children, and adolescents. Focus areas include addressing the need for additional STI prevention methods for women and curbing the rise in congenital syphilis cases.
Science Update: Positive parenting may counteract children’s biological aging in the face of adversity, NIH-funded study suggests
Positive parenting practices, like praising, noticing, and encouraging children’s behavior, may help reduce the faster rate of biological aging seen in children under adverse conditions. Such positive parenting practices may counter the effects of children’s hardships, improving their long-term physical and psychological health.
Science Update: Preterm infants fed donor milk had fewer intestinal complications than formula-fed infants
Compared to formula fed infants, extremely preterm infants fed donated human milk had half the rate of necrotizing enterocolitis, a life threatening condition of the intestines. There were no differences in neurological development between those fed donor milk and those fed formula.
Science Update: Preterm infants protected by maternal COVID-19 vaccination, NIH-funded study suggests
Preterm infants born to people who have been vaccinated for COVID-19 had roughly the same levels of antibodies to the spike protein of SARS-CoV-2 as term infants born to vaccinated people, allaying concerns that fewer antibodies might pass to preterm infants.