Transgenic expression of a dominant negative TR (dnTR)

Transgenic expression of a dominant negative TR (dnTR) inhibits TH-induced morphological changes. Wild type (WT) or transgenic tadpoles expressing dnTR under control of the CMV promoter (dnTR) were treated at premetamorphic stage 54 with or without TH for 3 days and were examined for changes in external morphology.