March 27, 2019 (Noon–1:15 p.m. ET)
Obstetric and Pediatric Pharmacology and Therapeutics Branch (OPPTB), Best Pharmaceuticals for Children Act, NICHD
In this webinar, Charles Berde, M.D., Ph.D., will review: ontogeny of peripheral, spinal, and central pathways involved in pain perception, pain modulation, and analgesia; age-related trends in the pharmacokinetics (PK) and pharmacodynamics (PD) of several classes of analgesics in pediatrics; scientific, ethical, and practical challenges in the conduct of pediatric analgesic trials; and selected areas of current research interest.
Participants of Dr. Berde’s lecture will:
- Improve their understanding of the development of pain pathways and analgesic actions in newborns, infants, and children.
- Increase their knowledge of age-related changes in PK and PD for several commonly used classes of analgesics and implications for dose selection and assessment of benefits and risks.
- Appreciate the challenges inherent in pediatric analgesic clinical trials and awareness of ongoing efforts to improve on pediatric analgesic study designs.
- Appreciate the status of several areas of active research on pediatric pain and analgesic pharmacology.
Dr. Berde is the Sara Page Mayo chair in pediatric pain medicine and chief of the Division of Pain Medicine at Boston Children's Hospital as well as professor of anaesthesia (pediatrics) at Harvard Medical School.
George Giacoia, OPPTB, NICHD