Prevention And Treatment through a Comprehensive Care Continuum for HIV-affected Adolescents in Resource Constrained Settings (PATC3H)

In 2022 and 2023, NIH published new Requests for Applications (RFAs) that will form the PATC3H Implementation Science Network (PATC3H-IN): RFA-HD-23-013: PATC3H-IN: Clinical Research Centers (UG1 Clinical Trial Optional) and RFA-HD-24-009: PATC3H-IN: Implementation Science Coordinating Center (UM2 Clinical Trial Optional).

Please note: RFA-HD-24-009 for a PATC3H-IN Implementation Science Coordinating Center has an application due date of December 6, 2023, and an optional Letter of Intent due date of November 6, 2023.

The PATC3H-IN Network Frequently Asked Questions page offers additional information about these RFAs as well as accompanying informational slides about this new network.


PATC3H logoFormed in 2018, PATC3H is a consortium of research teams external link that conducts clinical research and evaluations of a variety of combination interventions aimed at the individual, family, community, structural and education, and health systems levels, to improve health outcomes among adolescents with or at risk for HIV.

PATC3H’s primary goal is to generate the needed scientific innovation that will yield effective public health interventions for 10- to 24-year-olds (with emphasis on those age 20 or younger) affected by HIV in resource-limited settings of Brazil and sub-Saharan Africa. The program explores needs and interventions that may help reduce the HIV incidence rates among adolescents, while maximizing the impact of research in adolescent prevention and care for youth with HIV within these countries.

PATC3H is funded through the NICHD Maternal and Pediatric Infectious Disease Branch, the National Institute on Minority Health and Health Disparities, the Office of Behavioral and Social Sciences Research, and the Office of AIDS Research.

Current Studies

PATC3H study programs include the following:

More Information

Need data? PATC3H studies are now available in NICHD’s Data and Specimen Hub (DASH). Browse studies and request data for your research.
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