News

Small NIH study contributes to understanding of COVID-19 during pregnancy.

An individual’s risk for death by suicide may begin before they are born, suggests a study by researchers at the National Institutes of Health. The authors compared pregnancy and birth records of nearly 50,000 individuals born between 1959 and 1966 to death records through 2016. They found that suicide rates were higher for males, white people, and for those who were among the younger siblings in a family. Other risk factors included having a parent with less than a high school education, having a parent who worked a manual labor job, and having a mother with a high rate of pregnancy complications or who smoked during pregnancy.

Read about NICHD’s research findings and activities from 2021.

Sleep-disordered breathing in early pregnancy is associated with insulin resistance or difficulty clearing glucose from the blood, suggests a small study funded by the National Institutes of Health. The results strengthen the link between sleep-disordered breathing, which includes pauses or slowing of breathing during sleep, and gestational diabetes. They also suggest that screening pregnant women, particularly those with overweight or obesity, for sleep-disordered breathing could identify those who might benefit from early interventions to reduce their diabetes risk.

Pregnant women with disabilities have a much higher risk for severe pregnancy- and birth-related complications and death than other pregnant women, according to findings by researchers at the National Institutes of Health. Appearing in JAMA Network Open, the analysis of more than 223,000 deliveries in 19 U.S. hospitals found that roughly 2,199 women had a disability.

It just got easier to participate in the PregSource®: Crowdsourcing to Understand Pregnancy research project. The free app allows participants to track their weight, sleep, mood, and other features of their pregnancy in just a few taps.

Dr. Bianchi discusses NICHD-led research on long COVID in children.

Awarded projects seek to reduce pregnancy complications and prevent maternal deaths.

Dr. Grewal has been acting director of the division since February 2020.

The National Institutes of Health will support a four-year follow-up study on the potential long-term effects of COVID-19 on women infected with SARS-CoV-2 during pregnancy. The study will also follow their offspring for any potential long-term effects.

As we usher in November and Thanksgiving, it’s a fitting time to reflect on NICHD’s commitment to research on nutrition.

Episodes of maternal stress or depression during pregnancy are associated with chemical modifications to placental genes, according to a study by researchers from the National Institutes of Health. The modifications involve DNA methylation—binding of compounds known as methyl groups to DNA—which can alter a gene’s activity. Some of the methylation changes associated with maternal depression occurred near genes involved in brain development, suggesting that maternal depression in pregnancy could have long-term implications for the mental development of the child.

NIH-supported program reduces maternal deaths, complications in rural Guatemalan communities.

An antibody treatment in early pregnancy for women infected with cytomegalovirus does not appear to reduce the risk of infection or death among their newborns, an NIH-funded study suggests. The findings contradict several smaller studies on the treatment, known as hyperimmune globulin, that suggested the treatment was effective.

Drinking alcohol and smoking tobacco cigarettes throughout the first trimester of pregnancy is associated with nearly three times the risk of late stillbirth (at 28 or more weeks), compared to women who neither drink nor smoke during pregnancy or quit both before the end of the first trimester, according to a study funded by the National Institutes of Health.

Racial and ethnic disparities in maternal mortality in the United States may be larger than previously reported, suggests an NICHD-funded study.

A panel of experts convened by NICHD has recommended standardized criteria to define infection of the placenta with SARS-CoV-2, the virus that causes COVID-19. Their recommendations aim to help streamline research on SARS-CoV-2 infection during pregnancy and ultimately optimize clinical care.

Preemptive treatment for a nonviable pregnancy of unknown location resolves the condition more rapidly than treating symptoms as they arise, suggests an NICHD-supported study. However, both treatment approaches convey similar risks of adverse events.

The National Institutes of Health will award up to $400,000 to individuals or groups who design an effective method for analyzing a large data set of first-time pregnancies and identifying risk factors for adverse outcomes, such as hypertensive disorders, diabetes and infection. A total of $50,000 will be awarded to each of seven winners designing the most effective means to analyze the data. An additional $10,000 will be awarded to the top five winners whose methods identify risk factors in disadvantaged populations.

Dr. Bianchi reflects on the life and contributions of Eunice Kennedy Shriver ahead of Mrs. Shriver’s 100th birthday and how improving equity, diversity, and inclusion at NICHD continues Mrs. Shriver’s work.