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Infographic: Pediatric Drug Research at NICHD

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Infographic: Pediatric Drug Research at NICHD

Kids aren’t just little adults.

Drugs approved for adults may not fit kids’ needs.

Why?
Compared to adults, children:

  • Absorb and eliminate drugs from
    their bodies differently
  • Can experience different side effects
  • May require different drug formulations

Most drugs used in kids today have been tested only on adults. Researchers are testing these drugs on kids to answer questions about:

  • Safety
  • Dosing
  • Formulation
  • Efficacy

Since 1998, research—including NICHD-supported studies—has guided the safe and effective use of more than 400 medications in kids.

Spotlight on NICHD Research

An NICHD-funded study on meropenem—an antibiotic approved to treat infection in adults and older children—tested the drug in infants and found that:

  • Infants needed dosing adjustments based on prematurity and time after birth.
  • The drug was not associated with increased risk for serious side effects.


Meropenem is now FDA approved to treat abdominal infection in infants younger than 3 months.
New guidelines ensure safe and effective dosing.

Learn more about pediatric drug research at NICHD.

http://nichd.nih.gov

References:


Infographic PDF (750 KB) | Infographic JPG (1.5 MB)




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