Selecting the Right Dose for Pregnant Women Using Physiologically Based Pharmacokinetics (PBPK)

June 18, 2020 (Noon–1:30 p.m. ET)

Sponsor/Co-Sponsor(s)

Obstetric and Pediatric Pharmacology and Therapeutics Branch (OPPTB), Division of Extramural Research (DER), NICHD  

Location

Webinar; see “More Information” for how to register

Purpose

Decisions on medication use in pregnant women are often made with little or no clinical knowledge of a drug's effects in this population. Such knowledge is extremely difficult to generate through the conduct of clinical studies.

In this webinar, Ping Zhao, Ph.D., will discuss how PBPK models integrate drug-specific and physiology information, and how these models have been used in drug development to address a wide range of dose selection questions.

Dr. Zhao will focus on the following:

  • Why PBPK plays indispensable roles in selecting dose in pregnant women
  • How to use PBPK modeling to predict drug exposure in pregnant women
  • When to apply PBPK modeling to support dose selection in pregnant women
  • What efforts at Bill & Melinda Gates Foundation are ongoing to enable broader use of PBPK

Dr. Zhao is a senior program officer of integrated development-quantitative sciences with the Bill & Melinda Gates Foundation.

More Information

Learn more about this webinar external link and register to attend external link.

Contact

Individuals who have registered for a prior Sumner J. Yaffe webinar external link should contact bpca@infinityconferences.com to modify their existing registration to include this webinar.

For assistance with sign language interpreters and/or other reasonable accommodations to participate in this event:

George Giacoia, OPPTB, DER, NICHD
Phone: 301–496–5589
Email: giacoiag@mail.nih.gov

TTY users can call through the Federal Relay Service at 1-800-877-8339.

top of pageBACK TO TOP