June 18, 2020 (Noon–1:30 p.m. ET)
Obstetric and Pediatric Pharmacology and Therapeutics Branch (OPPTB), Division of Extramural Research (DER), NICHD
Webinar; see “More Information” for how to register
Decisions on medication use in pregnant women are often made with little or no clinical knowledge of a drug's effects in this population. Such knowledge is extremely difficult to generate through the conduct of clinical studies.
In this webinar, Ping Zhao, Ph.D., will discuss how PBPK models integrate drug-specific and physiology information, and how these models have been used in drug development to address a wide range of dose selection questions.
Dr. Zhao will focus on the following:
- Why PBPK plays indispensable roles in selecting dose in pregnant women
- How to use PBPK modeling to predict drug exposure in pregnant women
- When to apply PBPK modeling to support dose selection in pregnant women
- What efforts at Bill & Melinda Gates Foundation are ongoing to enable broader use of PBPK
Dr. Zhao is a senior program officer of integrated development-quantitative sciences with the Bill & Melinda Gates Foundation.
For assistance with sign language interpreters and/or other reasonable accommodations to participate in this event:
George Giacoia, OPPTB, DER, NICHD
TTY users can call through the Federal Relay Service at 1-800-877-8339.