Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at OPM.gov.

Selecting the Right Dose for Pregnant Women Using Physiologically Based Pharmacokinetics (PBPK)

June 18, 2020 (Noon–1:30 p.m. ET)

Sponsor/Co-Sponsor(s)

Obstetric and Pediatric Pharmacology and Therapeutics Branch (OPPTB), Division of Extramural Research (DER), NICHD  

Location

Webinar; see “More Information” for how to register

Purpose

Decisions on medication use in pregnant women are often made with little or no clinical knowledge of a drug's effects in this population. Such knowledge is extremely difficult to generate through the conduct of clinical studies.

In this webinar, Ping Zhao, Ph.D., will discuss how PBPK models integrate drug-specific and physiology information, and how these models have been used in drug development to address a wide range of dose selection questions.

Dr. Zhao will focus on the following:

  • Why PBPK plays indispensable roles in selecting dose in pregnant women
  • How to use PBPK modeling to predict drug exposure in pregnant women
  • When to apply PBPK modeling to support dose selection in pregnant women
  • What efforts at Bill & Melinda Gates Foundation are ongoing to enable broader use of PBPK

Dr. Zhao is a senior program officer of integrated development-quantitative sciences with the Bill & Melinda Gates Foundation.

More Information

Learn more about this webinar external link and register to attend external link.

Contact

Individuals who have registered for a prior Sumner J. Yaffe webinar external link should contact bpca@infinityconferences.com to modify their existing registration to include this webinar.

For assistance with sign language interpreters and/or other reasonable accommodations to participate in this event:

George Giacoia, OPPTB, DER, NICHD
Phone: 301–496–5589
Email: giacoiag@mail.nih.gov

Please note: Views expressed during NICHD-sponsored events do not necessarily reflect the opinions or the official positions of NICHD, NIH, or HHS.
top of page BACK TO TOP