Program seeks Council approval for an initiative entitled “Small Research Grants for Analyses of Gabriella Miller Kids First Pediatric Research Data”.
The NIH Common Fund has established the Gabriella Miller Kids First Pediatric Research Program (Kids First) to develop a pediatric research data resource containing genome sequence and phenotype data that will be of high value for the communities of investigators who study the genetics of childhood cancers and/or structural birth defects. The goal of the Gabriella Miller Kids First Pediatric Data Resource is to build a collection of curated genomic and phenotypic data from childhood cancer and birth defects cohorts and provide a central portal where data and analysis tools will be readily accessible to the research community.
This is a reissue of a previous funding opportunity announcement (FOA). NICHD, with participation from NCI, NHLBI, NIAAA, NIDCR and NINDS, supported this earlier FOA which resulted in 8 awards: 2 by NIDCR, 2 by NCI, 2 by NHLBI, and 2 by NICHD. As additional Kids First datasets are released to the public, we anticipate the proposed initiative will be increasingly used by researchers to support analysis projects.
This initiative is intended to support meritorious small research projects focused on the development and analyses of childhood cancer and/or structural birth defects datasets that are part of the Kids First Data Resource or could be included in the Kids First Data Resource. Development of statistical methodology appropriate for analyzing genome-wide data relevant to childhood cancer and/or structural birth defects may also be supported.
This proposed concept aligns with the NICHD vison area goal “to predict, identify and ameliorate the steps leading to birth defects and other variations in human structure and functioning”.
This proposed concept aligns with the Branch Priority of developing tools for studying embryonic development and birth defects.
The proposed concept is intended to stimulate the research communities’ use of the recently established Kids First Data Resource and cloud-based computational analysis tools and environment. Access to these data and analysis tools will promote comprehensive and cross-cutting research and collaboration leading to more refined diagnostic capabilities and ultimately more targeted therapies.
Program Contact
James Coulombe
Developmental Biology and Structural Variation Branch (DBSVB)
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