201801 Using Archived Data and Specimen Collections to Advance Maternal and Pediatric HIV/AIDS Research

A long-standing goal of Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is to maximize research, resources and tools. To meet this need, the Maternal and Pediatric Infectious Disease Branch (MPIDB) is seeking approval for a FY 19 initiative titled “Using Archived Data and Specimen Collections to Advance Maternal and Pediatric HIV/AIDS Research.” 

The purpose of this Funding Opportunity Announcement (FOA) directly addresses the scientific community and need for improved data sharing and translation of research results to answer important questions in maternal and pediatric HIV.  Specifically, this initiative proposes to further maximize the utility of HIV/AIDS clinical, epidemiological, behavioral and other studies’ data and specimens through secondary analyses.  

The NICHD repository has held a long-established and critical role in the collection of HIV/AIDS specimens.  Home to six large-scale studies or networks ranging in complexity and specimen type, there is a rich collection of archived bio-samples available for study. In addition, the NICHD Data and Specimen Hub (DASH) stores and provides access to the phenotypic data linked to these bio-samples, as well as access to additional phenotypic and specimen archives for other NICHD funded studies, including the AIDS Clinical Research Trials Group (ACTG) International Maternal and Pediatric Adolescent AIDS Clinical Trials (IMPAACT) – home to over 30 types and a total of 3 million specimens combined.

To maximize the utility and scientific potential of these valuable resources, this initiative will encourage the scientific community to use the archived specimens and phenotypic data to generate new findings and answer novel research questions related to the scientific mission and priorities of NICHD, MPIDB, and the Office of AIDS Research (OAR). 

In a highly data driven world, the translation and future development of HIV/AIDS data in maternal and child health is critical.  To continue with advancements in the analysis, translation and dissemination of research findings, this initiative will encourage all new data derived from this initiative’s analyses to be returned to DASH.

Program Contact

Denise Russo
Maternal and Pediatric Infectious Disease Branch

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