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Appendix B

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Table 6. Relationship of Phenylalanine Hydroxylase Mutation to their Adult WAIS-R Intelligence Quotient Regardless of Parental IQ, Age of Diagnosis, and Treatment History

Mutation Severity
Number Median WAIS-R
Severe/Severe 31 95 (n=30)
Severe/Moderate 15 100
Severe/Mild 4 101
Severe/Unclassified 4 100
Moderate/Unclassified 1 80
In Process 11 89 (n=9)
Both Mutations Unclassified 1 116

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Last Reviewed: 08/29/2006
Vision National Institutes of Health Home BOND National Institues of Health Home Home Storz Lab: Section on Environmental Gene Regulation Home Machner Lab: Unit on Microbial Pathogenesis Home Division of Intramural Population Health Research Home Bonifacino Lab: Section on Intracellular Protein Trafficking Home Lilly Lab: Section on Gamete Development Home Lippincott-Schwartz Lab: Section on Organelle Biology