News & Updates

The basic research effort to implicate soluble endoglin (sEng) and soluble fms-like tyrosine kinase 1 (sFlt-1) in preeclampsia was led by a coauthor of the current paper, S. Ananth Karumanchi, M.D., a nephrologist at the Beth Israel Deaconess Medical Center in Boston.

Contrary to prevailing medical opinion, taking high doses of calcium during pregnancy does not prevent preeclampsia in women who do not have any risk factors for the disease, according to the largest, most comprehensive clinical trial of its kind to date.

A drug first used to reduce the risk of stomach ulcers in people taking certain types of painkillers offers an alternative to surgery after miscarriage, according to a study by researchers at the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health and other research institutions.

The risks from vaginal delivery after a prior Cesarean delivery are low, but are slightly higher than for a repeat Cesarean delivery. This finding is from the largest, most comprehensive study of its kind ever conducted, undertaken by the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health.

Pregnant women who are overweight or obese progress through labor more slowly than do normal weight women, according to a study by researchers at the University of North Carolina and the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health.

An NIH roadmap initiative will provide a total of nearly $8 million in funding to seven institutions that can train researchers in multidisciplinary research-research involving teams of specialists from a variety of disciplines.

A single dose of the drug nevirapine given at the beginning of labor, when combined with a short course of the anti-HIV drug AZT (zidovudine), dramatically reduces a woman's chances of passing HIV on to her child, according to a study of Thai women funded in part by the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health.

Multivitamin supplements containing high doses of the vitamin B complex, as well as vitamins C and E, given to HIV-infected women during pregnancy and for more than 5 years after they gave birth reduced the symptoms of AIDS, according to a study of Tanzanian women supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and the John E. Fogarty International Center (FIC) for Advanced Study in the Health Sciences, both of the National Institutes of Health.

A team of researchers has discovered a gene for Cornelia de Lange Syndrome, a disorder consisting of mental retardation, heart defects and a number of physical abnormalities.

Newborns whose mothers drank alcohol heavily during pregnancy had damage to the nerves in the arms and legs, according to a study by researchers at the Eunice Kennedy Shriver National Institute of Child Health and Human Development, one of the National Institutes of Health.

One of the National Institutes of Health has begun a concerted effort to determine the extent and causes of stillbirth- the death of a fetus at 20 or more weeks of pregnancy.

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) has selected the first eight research units for the Global Network for Women's and Children's Health Research, an international research network to improve the health of women and children throughout the world.

Researchers funded by the National Institutes of Health have discovered how an embryo initially attaches to the wall of the uterus-what appears to be one of the earliest steps needed to establish a successful pregnancy.

Pregnant women who have low blood levels of the vitamin folate are more likely to have early miscarriages than are pregnant women who have adequate folate levels, according to a study of Swedish women by researchers at the Karolinska Institutet in Sweden and at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

Two experimental compounds prevent one of the cellular events that is a likely contributor to fetal alcohol syndrome (FAS), according to a new study supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA).

In contrast to the pattern seen with singleton births, twins born to older mothers do not appear to have a greater risk of birth complications than do twins born to younger mothers, according to a recent study by researchers at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and the University of Kansas.

Portable monitors that detect contractions of the uterus do not appear to be useful for identifying women likely to have a preterm delivery, according to a study by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

A sharp drop in stress hormones after giving birth to a child may predispose some women to develop certain conditions in which the immune system attacks the body's own tissues, according to researchers at the National Institutes of Health.

A short cervix early in the second trimester of pregnancy appears to be a warning sign of impending premature birth among women who have previously given birth prematurely, according to a study by the Eunice Kennedy Shriver National Institute of Child Health and Human Development's (NICHD) Maternal Fetal Medicine Units (MFMU) Network.

Using the drug metronizadole to treat pregnant women who have the sexually transmitted disease trichomoniasis does not reduce the women's chances for giving birth prematurely, and may actually increase them, according to a study appearing in the August 16 New England Journal of Medicine.