Publications

2019

  • Akgül G., Abebe D., Yuan X.Q., Auville K. and C.J. McBain. 2019. The Role of AMPARs in the Maturation and Integration of Caudal Ganglionic Eminence-Derived Interneurons into Developing Hippocampal Microcircuits. Sci. Rep. Apr 1;9(1):5435. doi: 10.1038/s41598-019-41920-9. PMID: 30931998.
  • Appu A.P., Bagh M.B., Sadhukhan T., Mondal A., Casey S. and A.B. Mukherjee. 2019. Cln3-mutations underlying juvenile NCL cause significantly reduced levels of Ppt1-protein and Ppt1-enzyme activity in the lysosome. J. Inherit. Metab. Dis. Apr 26. doi: 10.1002/jimd.12106. [Epub ahead of print]
  • Baba T., Toth D.J., Sengupta N., Kim Y.J. and T. Balla. 2019. Phosphatidylinositol 4,5-bisphosphate controls Rab7 and PLEKMH1 membrane cycling during autophagosome-lysosome fusion. EMBO J. 2019 Apr 15;38(8). pii: e100312. doi: 10.15252/embj.2018100312. Epub 2019 Mar 13. PMID: 30867165
  • Coon S.L., Fu C., Hartley S.W., Holtzclaw L., Mays J.C., Kelly M.C., Kelley M.W., Mullikin J.C., Rath M.F., Savastano L.E. and D.C. Klein. 2019. Single Cell Sequencing of the Pineal Gland: The Next Chapter. Front. Endocrinol. 10:590. doi: 10.3389/fendo.2019.00590
  • Erben L. and A. Buonanno. 2019. Detection and Quantification of Multiple RNA Sequences Using Emerging Ultrasensitive Fluorescent In Situ Hybridization Techniques. https://doi.org/10.1002/cpns.63 .
  • Hunter G.L., He L., Perrimon N., Charras G., Giniger E. and B.A. Baum. 2019. A role for actomyosin contractility in Notch signaling. BMC Biol. 2019 Feb 11;17(1):12. doi: 10.1186/s12915-019-0625-9. PMID: 30744634
  • Li L., Yang Z., Zhu S., He. L., Fan W., Tang W., Zou J., Shen Z., Zhang M., Tang L., Dai Y., Niu G., Hu S. and X. Chen. 2019. A Rationally Designed Semiconducting Polymer Brush for NIR-II Imaging-Guided Light-Triggered Remote Control of CRISPR/Cas9 Genome Editing. Advanced Materials. https://doi.org/10.1002/adma.201901187 
  • Niu G., Rong P., Wang W. and X. Chen. 2019. Stimuli-Responsive Nanotheranostics for Real-Time Monitoring Drug Release by Photoacoustic Imaging. Theranostics 2019, Vol. 9, Issue 2
  • Papp F., Lomash S., Szilagyi O., Babikow E., Smith J., Chang T.H., Bahamonde M.I., Toombes G.E. and K. Swartz. 2019. TMEM266 is a functional voltage sensor regulated by extracellular Zn2. Elife. 2019 Feb 27;8. pii: e42372. doi: 10.7554/eLife.42372.
  • Wang S., Zhou Z., Wang Z., Liu Y., Jacobson O., Shen Z., Fu X., Chen Z.Y. and X. Chen. 2019. Gadolinium Metallofullerene-Based Activatable Contrast Agent for Tumor Signal Amplification and Monitoring of Drug Release. Small 2019, 15 (16), 1900691.
  • Wester J.C., Mahadevan V., Rhodes C., Calvigioni D., Vankatesh S., Maric D., Hunt S., Yuan X., Zhang Y., Petros T.J. and C.J. McBain. 2019. Neocortical projection neurons instruct inhibitory interneuron circuit development in a lineage dependent manner. Neuron (in press).
  • Xiao L., Yang X., Sharma V.K. and Y.P. Loh. 2019. Cloning, gene regulation, and neuronal proliferation functions of novel N-terminal-truncated carboxypeptidase E/neurotrophic factor-al variants in embryonic mouse brain. FASEB J. Jan;33(1):808-820. doi: 10.1096/fj.201800359R. Epub 2018 Jul 31.Yang Z., Song J., Tang W., Fan W., Dai Y., Shen Z., Lin L., Cheng S., Liu Y.

2018

  • Alvarez-Prats A., Bjelobaba I., Aldworth Z., Baba T., Abebe D., Kim Y.J., Stojilkovic S.S., Stopfer M. and T. Balla.. 2018. Schwann-Cell-Specific Deletion of Phosphatidylinositol 4-Kinase Alpha Causes Aberrant Myelination. Cell Reports, 23:  2881-2890.
  • Ballesteros A., Fenollar-Ferrer C. and K.J. Swartz. 2018. Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins. eLife 2018;7:e38433 doi: 10.7554/eLife.38433
  • Dutta B.J., Woo D.H., Lee P.R., Pajevic S., Bukalo O., Huffman W.C., Wake H., Basser P.J., SheikhBahaei S., Lazarevic V., Smith J.C and R.D. Fields. 2018. Regulation of myelin structure and conduction velocity by perinodal astrocytes. PNAS November 13, 115, 46: 11832-11837
  • Erben L., He M.X., Laeremans A., Park E. and A. Buonanno. 2018. A Novel Ultrasensitive In Situ Hybridization Approach to Detect Short Sequences and Splice Variants with Cellular Resolution. Mol Neurobiol. 2018 Jul;55(7):6169-6181. doi: 10.1007/s12035-017-0834-6. Epub 2017 Dec 20. PMID: 29264769.
  • Haddad M.R., Choi E.Y., Zerfas P.M., Yi L., Martinelli D., Sullivan P., Goldstein D.S., Centeno J.A., Brinster L.R., Ralle M. and S.G. Kaler. 2018. Cerebrospinal Fluid-Directed rAAV9-rsATP7A Plus Subcutaneous Copper Histidinate Advance Survival and Outcomes in a Menkes Disease Mouse Model. Molecular Therapy: Methods & Clinical Development Vol. 10, p. 165-178
  • Hunter G., He L., Perrimon N., Charras G., Giniger E. and B. Baum. 2018. Long-range Notch-mediated tissue patterning requires actomyosin contractility. bioRxiv259341;doi: https://doi.org/10.1101/259341 
  • Lin L., Murphy J.G., Karlsson R.M., Petralia R.S., Gutzmann J.J., Abebe D., Wang Y.X, Cameron H.A and D.A. Hoffman. 2018. DPP6 Loss Impacts Hippocampal Synaptic Development and Induces Behavioral Impairments in Recognition, Learning and Memory. Front. Cell. NeuroSci. doi: 10.3389/fncel.2018.00084
  • Mays J.C., Kelly M.C., Coon S.L., Holtzclaw L.A., Rath M.F., Kelley M.W. and D.C. Klein. 2018. Single-cell RNA sequencing of the mammalian pineal gland identifies two pinealocyte subtypes and cell type-specific daily patterns of gene expression. PLOS. https://doi.org/10.1371/journal.pone.0205883 .
  • McCormick C.D., Waters H.N., Bezrukov L., Taginya R., Parikh V., Onyekaba G.I., Levine J.A., Demidowich A.P., Yanovski J.A., Blank P.S. and J. Zimmerberg. 2018. Subcutaneous adipose tissue imaging of human obesity reveals two types of adipocyte membranes: Insulin-responsive and -nonresponsive. J. Biol. Chem. Sep 14;293(37):14249-14259. doi: 10.1074/jbc.RA118.003751. Epub 2018 Jul 13.
  • Skirzewski M., Karavanova I., Shamir A., Erben L., Garcia-Olivares J., Shin J.H., Vullhorst D., Alvarez V.A., Amara S.G. and A. Buonanno. 2018. ErbB4 signaling in dopaminergic axonal projections increases extracellular dopamine levels and regulates spatial/working memory behaviors. Mol Psychiatry. Nov;23(11):2227-2237. doi: 10.1038/mp.2017.132. Epub 2017 Jul 20. PMID: 28727685
  • Sohn M., Korzeniowski M., Zewe J.P., Wills R.C., Hammond G.R.V., Humpolickova J., Vrzal L., Chalupska D., Veverka V., Fairn G.D., Boura E. and T. Balla. 2018. P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites. J. Cell. Biol. May 7;217(5):1797-1813. doi: 10.1083/jcb.201710095. Epub 2018 Feb 22. PMID: 29472386
  • Wang Q., Han H.T., Ngyuen P., Jarnik M. and M. Serpe. 2018. Tenectin recruits integrin to stabilize bouton architecture and regulate vesicle release at the Drosophila neuromuscular junction. eLife 2018; 7: e35518.
  • Wlaschin J.J., Gluski J.M., Nguyen E., Silberberg H, Thompson J.H., Chesler A.T. and C.E. Le Pichon. 2018. Dual leucine zipper kinase is required for mechanical allodynia and microgliosis after nerve injury. eLife 2018;7:e33910 doi: 10.7554 / eLife.33910.
  • Yamano K., Wang C., Sarraf S.A., Münch C., Kikuchi R., Noda N.N., Hizukuri Y., Kanemaki M.T., Harper W., Tanaka K. Matsuda N. and R.J. Youle. 2018. Endosomal Rab cycles regulate Parkin-mediated mitophagy. Jan 23;7. pii: e31326. doi: 10.7554/eLife.31326.
  • Yi L. and S.G.. Kaler. 2018. Interaction between the AAA ATPase p97/VCP and a concealed UBX domain in the copper transporter ATP7A is associated with motor neuron degeneration. JBC Papers in Press. Published on March 29, 2018 as Manuscript RA117.000686.
  • Zhou Z., Chan A., Wang Z., Huang X., Yu G., Jacobson O., Wang S., Liu Y., Shan L., Dai Y., Shen Z., Lin L., Chen W. and X. Chen. 2018. Synchronous Chemoradiation Nanovesicles by X-Ray Triggered Cascade of Drug Release Angewandte Chemie, 130 (28), 8599-8603.

2017

  • Angelousi A., Szarek E., Schram V., Kebebew E., Quezado M. and C.A. Stratakis. 2017. Lipofuscin Accumulation in Cortisol-Producing Adenomas With and Without PRKACA Mutations. Horm Metab Res. Aug 23. doi: 10.1055/s-0043-116385.
  • Bagh M.B., Peng S., Chandra G., Zhang Z., Singh S.P., Pattabiraman N., Liu A. and A.B. Mukherjee. 2017. Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model. Nat Commun. 2017 Mar 7;8:14612. doi: 10.1038/ncomms14612.
  • Berthon A., Faucz F.R., Espiard S., Drougat L., Bertherat J. and StratakisC.A. Age-dependent effects of Armc5 haploinsufficiency on adrenocortical function. Human Molecular Genetics, 2017, Vol. 26, No. 18 3495–3507
  • Blewett N.H., Iben J.R., Gaidamakov S. and R.J. Maraia. 2017. La Deletion from Mouse Brain Alters Pre-tRNA Metabolism and Accumulation of Pre-5.8S rRNA, with Neuron Death and Reactive Astrocytosis. Mol Cell Biol. May 2;37(10). pii: e00588-16. doi: 10.1128/MCB.00588-16. Print 2017 May 15.
  • Burman J.L., Pickles S., Wang C., Sekine S., Vargas J.N.S., Zhang Z., Youle A.M., Nezich C.L., Wu X., Hammer J.A. and R.J. Youle. 2017. Mitochondrial fission facilitates the selective mitophagy of protein aggregates. J. Cell. Biol. Oct 2;216(10):3231-3247. doi: 10.1083/jcb.201612106. Epub 2017 Sep 11. PMID: 28893839.
  • Chittajallu R., Wester J.C., Craig M.T., Barksdale E., Yuan X.Q., Akgül G., Fang C., Collins D., Hunt S., Pelkey K.A. and C.J. McBain. 2017. Afferent specific role of NMDA receptors for the circuit integration of hippocampal neurogliaform cells. Nat Commun. 8(1):152. doi: 10.1038/s41467-017-00218-y.
  • Cho J.H., Kim G.Y., Pan C.J., Anduaga J., Choi E.J., Mansfield B. and J. Chou. 2017. Downregulation of SIRT1 signaling underlies hepatic autophagy impairment in glycogen storage disease type Ia. PLoS Genet. 2017 May; 13(5): e1006819.
  • Komlosh M.E., Benjamini D., Hutchinson E.B., King S., Haber M., Avram A.V., Holtzclaw L.A., Desai A., Pierpaoli C. and P.J. Basser. Using double pulsed-field gradient MRI to study tissue microstructure in traumatic brain injury (TBI). Microporous and Mesoporous Materials. 2017; In Press.
  • Korzeniowski M.K., Wisniewski E., Baird B., Holowka D. and T. Balla. 2017. Molecular anatomy of the early events in STIM1 activation; oligomerization or conformational change? J. Cel Sci. Jul 19. pii: jcs.205583. doi: 10.1242/jcs.205583. [Epub ahead of print]
  • Liu X., Campanac E., Cheung H.H., Ziats M.N., Canterel-Thouennon L., Raygada M., Baxendale V., Pang A.L., Yang L., Swedo S., Thurm A., Lee T.L., Fung K.P., Chan W.Y., Hoffman D.A. and O.W. Rennert. 2017. Idiopathic Autism: Cellular and Molecular Phenotypes in Pluripotent Stem Cell-Derived Neurons. Mol Neurobiol. 54(6):4507-4523. doi: 10.1007/s12035-016-9961-8.
  • Selvaraj P., Xiao L., Lee C., Murthy S.R., Cawley N.X., Lane M., Merchenthaler I., Ahn S. and Y.P. Loh. 2017. Neurotrophic Factor-a1: A Key Wnt-ß-Catenin Dependent Anti-Proliferation Factor and ERK-Sox9 Activated  Inducer of Embryonic Neural Stem Cell Differentiation to Astrocytes in Neurodevelopment. Stem Cells. Mar;35(3):557-571. doi: 10.1002/stem.2511. Epub 2016 Oct 26.
  • Shimizu K. and M. Stopfer. 2017. A Population of Projection Neurons that Inhibits the Lateral Horn but Excites the Antennal Lobe through Chemical Synapses in Drosophila. Front Neural Circuits. 2017 May 3;11:30. doi: 10.3389/fncir.2017.00030. eCollection 2017. Erratum in: Front Neural Circuits. 2018 Jun 20;12:49. PMID: 28515683
  • Skirzewski M., Karavanova I , Shamir A , Erben L , Garcia-Olivares J , Shin J H , Vullhorst D , Alvarez V A , Amara S G and A. Buonanno. 2017.ErbB4 signaling in dopaminergic axonal projections increases extracellular dopamine levels and regulates spatial/working memory behaviors. Mol. Psychiatry. Jul 20. doi: 10.1038/mp.2017.132. [Epub ahead of print]
  • Stratman A.N., Pezoa S.A., Farrelly O.M., Castranova D., Dye L.E. 3rd, Butler M.G., Sidik H., Talbot W.S. and B.M. Weinstein. . 2017. Interactions between mural cells and endothelial cells stabilize the developing zebrafish dorsal aorta. Development .144: 115-127; doi:10.1242/dev.143131
  • Valm A.M., Cohen S., Legant W.R., Melunis J., Hershberg U., Wait E., Cohen A.R., Davidson M.W., Betzig E. and J. Lippincott-Schwartz. 2017. Applying systems-level spectral imaging and analysis to reveal the organelle interactome. Nature ; 546: 162–167.
  • Várnai P., Gulyás G., Tóth D.J. Sohn M., Sengupta N. and T. Balla. 2017. Quantifying lipid changes in various membrane compartments using lipid binding protein domains. Cell Calcium. 64: 72-82. doi: 10.1016/j.ceca.2016.12.008. Epub 2016 Dec 31.
  • Vullhorst D., Ahmad T., Karavanova I., Keating C. and A. Buonanno. 2017. Structural Similarities between Neuregulin 1-3 Isoforms Determine Their Subcellular Distribution and Signaling Mode in Central Neurons. J Neurosci. 37(21):5232-5249. doi: 10.1523/JNEUROSCI.2630-16.2017.
  • Yan L., Shamir A., Skirzewski M., Leiva-Salcedo E., Kwon O.B., Karavanova I., Paredes D., Malkesman O., Bailey K.R., Vullhorst D., Crawley J.N. and A. Buonanno A. 2017. Neuregulin-2 ablation results in dopamine dysregulation and severe behavioral phenotypes relevant to psychiatric disorders. Mol. Psychiatry. 2018 May: 23(5):1233-1243. doi: 10.1038/mp.2017.22. Epub 2017 Mar 21.
  • Wyeth M.S., Pelkey K.A., Yuan X., Vargish G., Johnston A.D., Hunt S., Fang C., Abebe D., Mahadevan V., Fisahn A., Salter M.W., McInnes R.R., Chittajallu R. and C.J. McBain. 2017. Neto Auxiliary Subunits Regulate Interneuron Somatodendritic and Presynaptic Kainate Receptors to Control Network Inhibition. Cell Rep. 2017 Aug 29;20(9):2156-2168. doi: 10.1016/j.celrep.2017.08.017. PMID: 28854365.
  • Zhou Z., Song J., Tian R., Yang Z., Yu G., Lin L., Zhang G., Fan W., Zhang F., Niu G., Nie L. and X. Chen. 2017. Activatable Singlet Oxygen Generation from Lipid Hydroperoxide Nanoparticles for Cancer Therapy. Angewandte Chemie, 2017, 129 (23), 6492-6496.

2016

  • Awad K.S., Elinoff J.M., Wang S., Gairhe S., Ferreyra G.A., Cai R., Sun J., Solomon M.A. and R.L. Danner. 2016. Raf/ERK drives the proliferative and invasive phenotype of BMPR2-silenced pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol. Jan 15;310(2):L187-201.
  • Benjamini D., Komlosh M.E., Holtzclaw L.A., Nevo U. and P.J. Basser. 2016. White matter microstructure from nonparametric axon diameter distribution mapping. Neuroimage. 2016 Jul 15;135:333-44. doi: 10.1016/j.neuroimage.2016.04.052. Epub 2016 Apr 26.
  • Bhattacharjee A., Yang H., Duffy M., Robinson E., Conrad-Antoville A., Lu Y.W., Capps T., Braiterman L., Wolfgang M., Murphy M.P., Yi L., G. Kaler, Lutsenko S. and M. Ralle. 2016. The Activity of Menkes Disease Protein ATP7A Is Essential for Redox Balance in Mitochondria. J Biol Chem. Aug 5; 291(32): 16644–16658. Published online 2016 May 16. doi: 10.1074/jbc.M116.727248
  • Cawley N.X., Rathod T., Young S., Lou H., Birch N. and Y.P. Loh. 2016. Carboxypeptidase E and Secretogranin III Coordinately Facilitate Efficient Sorting of Proopiomelanocortin to the Regulated Secretory Pathway in AtT20 Cells. Molecular Endocrinology, Volume 30, Issue 1, 1 January 2016, Pages 37–47,
  • Cheng Y., Cawley N.X., Yanik T., Murthy S.R., Liu C., Kasikci F., Abebe D and Y.P. Loh. 2016. A human carboxypeptidase E/NF-α1 gene mutation in an Alzheimer's disease patient leads to dementia and depression in mice. Transl Psychiatry. 6(12):e973.
  • Kim Y.J., Guzman-Hernandez M.L., Wisniewski E., Echeverria N. and T. Balla. 2016. Phosphatidylinositol and phosphatidic acid transport between the ER and plasma membrane during PLC activation requires the Nir2 protein. Biochem Soc Trans. 2016 Feb;44(1):197-201. doi: 10.1042/BST20150187.
  • Klima M., Tóth D.J., Hexnerova R., Baumlova A., Chalupska D., Tykvart J., Rezabkova L., Sengupta N., Man P., Dubankova A., Humpolickova J., Nencka R., V. Veverka, Balla T. and E. Boura Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein. Sci Rep. 2016; 6: 23641. Published online 2016 Mar 24. doi: 10.1038/srep23641
  • Lin T.Y., Luo J., Shinomiya K., Ting C.Y., Lu Z., Meinertzhagen I.A. and C.H. Lee. 2016. Mapping chromatic pathways in the Drosophila visual system. J. Comp. Neurol. Feb 1;524(2):213-27. doi: 10.1002/cne.23857. Epub 2015 Aug 11. PMID: 26179639.
  • Linares G.R., Chiu C.T., Scheuing L., Leng Y, Liao H.M., Maric D and D.M. Chuang. Preconditioning mesenchymal stem cells with the mood stabilizers lithiumand valproic acid enhances therapeutic efficacy in a mouse model of Huntington's disease. Experimental Neurology 281 (2016) 81–92.
  • Mirigian L.S., Makareeva E., Mertz E.L., Omari S., Roberts-Pilgrim A.M., Oestreich A.K., Phillips C.L. and S. Leikin. 2016. Osteoblast Malfunction Caused by Cell Stress Response to Procollagen Misfolding in α2(I)-G610C Mouse Model of Osteogenesis Imperfecta.J Bone Miner Res. 31(8):1608-16.
  • Pelkey K.A., Barksdale E., Craig M.T., Yuan X., Sukumaran M., Vargish G.A., Mitchell R.M., Wyeth M.S., Petralia R.S., Chittajallu R., Karlsson R.M., Cameron H.A., Murata Y., Colonnese M.T., Worley P.F. and C.J. McBain. 2015. Pentraxins coordinate excitatory synapse maturation and circuit integration of parvalbumin interneurons. Neuron. 85(6): 1257–1272.
  • Sohn M., Ivanova P., Brown H.A., Toth D.J., Varnai P., Kim Y.J. and T. Balla. 2016. Lenz-Majewski mutations in PTDSS1 affect phosphatidylinositol 4-phosphate metabolism at ER-PM and ER-Golgi junctions. Proc Natl Acad Sci U S A. 113(16):4314-9. doi: 10.1073/pnas.1525719113. Epub 2016 Apr 4.
  • Wang Z., Leng Y., Wang J., Liao H.M., Bergman J., Leeds P., Kozikowski A. and D.M. Chuang. 2016 Tubastatin A, an HDAC6 inhibitor,alleviates stroke-induced brain infarction and functional deficits:potential roles of α-tubulin acetylation and FGF-21 upregulation. Scientific Reports 6, Article number: 19626. doi:10.1038/srep19626

2015

  • Bai R., Klaus A., Bellay T., Stewart C., Pajevic S., Nevo U., Merkle H., Plenz D. and P.J. Basser. 2015. Simultaneous calcium fluorescence imaging and MR of ex vivo organotypic cortical cultures: a new test bed for functional MRI. NMR Biomed. 2015 Dec;28(12):1726-38. doi: 10.1002/nbm.3424. Epub 2015 Oct 29.
  • Bojjireddy N., Guzman-Hernandez M.L., Reinhard N.R., Jovic M. and T. Balla. 2015. EFR3s are palmitoylated plasma membrane proteins that control responsiveness to G-protein-coupled receptors. J Cell Sci. 128: 118-128. Epub 2014 Nov 6.
  • Chandra G., Bagh M.B., Peng S., Saha A., Sarkar C., Moralle M., Zhang Z. and A.B. Mukherjee. 2015. Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disorders. Hum Mol Genet. pii: ddv266. [Epub ahead of print]
  • Cheng Y., Rodriguiz R.M., Murthy S.R., Senatorov V., Thouennon E., Cawley N.X., Aryal D.K., Ahn S., Lecka-Czernik B., Wetsel W.C. and Y.P. Loh. 2015. Neurotrophic factor-α1 prevents stress-induced depression through enhancement of neurogenesis and is activated by rosiglitazone. Mol Psychiatry. 20(6):744-54.
  • Choi E.Y., Patel K., Haddad M.R., Yi L., Holmes C., Goldstein D.S., Dutra A., Pak E. and S.G. Kaler. 2015. Tandem Duplication of Exons 1-7 Neither Impairs ATP7A Expression Nor Causes a Menkes Disease Phenotype. JIMD Rep. 20:57-63. doi: 10.1007/8904_2014_391. Epub 2015 Feb 1.
  • Hammond G.R.V., Takasuga S., Sasaki T. and T. Balla. 2015. The ML1Nx2 Phosphatidylinositol 3,5-Bisphosphate Probe Shows Poor Selectivity in Cells. PLoS One. 10(10): e0139957. Published online 2015 Oct 13. doi: 10.1371/journal.pone.0139957 PMCID: PMC4604148
  • Kim Y.J., Guzman-Hernandez M.L., Wisniewski E. and T. Balla. 2015. Phosphatidylinositol-Phosphatidic Acid Exchange by Nir2 at ER-PM Contact Sites Maintains Phosphoinositide Signaling Competence. Dev Cell. 33: 549-561. Epub 2015 May 28.
  • Kim Y.J., Igiesuorobo O., Ramos C.I., Bao H., Zhang B. and M. Serpe. 2015. Prodomain Removal Enables Neto to Stabilize Glutamate Receptors at the Drosophila Neuromuscular Junction, PLoS Genet 27;11(2):e1004988. Epub 2015 Feb 27.
  • London E., Wassif C.A., Horvath A., Tatsi C., Angelousi A., Karageorgiadis A.S., Porter F.D. and C.A. Stratakis. 2015. Cholesterol biosynthesis and trafficking in cortisol-producing lesions of the adrenal cortex. J Clin Endocrinol Metab. 2015 Jul 23:jc20152212. [Epub ahead of print]
  • Miyazaki T., Lin T.Y., Ito K., Lee C.H. and M. Stopfer. 2015. A gustatory second-order neuron that connects sucrose-sensitive primary neurons and a distinct region of the gnathal ganglion in the Drosophila brain. J Neurogenet. 29(0): 144–155. Published online 2015 Aug 27. doi: 10.3109/01677063.2015.1054993
  • Pelkey K.A., Barksdale E., Craig M.T., Yuan X., Sukumaran M., Vargish G.A., Mitchell R.M., Wyeth M.S., Petralia R.S., Chittajallu R., Karlsson R.M., Cameron H.A., Murata Y., Colonnese M.T., Worley P.F,. and C.J. McBain. 2015. Pentraxins coordinate excitatory synapse maturation and circuit integration of parvalbumin interneurons. Neuron. 85: 1257-1272. doi: 10.1016/j.neuron.2015.02.020. Epub 2015 Mar 5.
  • Peng S., Xu J., Pelkey K.A., Chandra G., Zhang Z., Bagh M.B., Yuan X., Wu L.G., McBain C.J. and A.B. Mukherjee. 2015. Suppression of agrin-22 production and synaptic dysfunction in Cln1−/− mice. Ann Clin Transl Neurol. 2(12): 1085–1104. Published online 2015 Nov 6. doi: 10.1002/acn3.261
  • Ramos C.I., Igiesuorobo O., Wang Q. and M. Serpe. 2015. Neto-Mediated Intracellular Interactions Shape Postsynaptic Composition at the Drosophila Neuromuscular Junction. PLoS Genet. 11(4): e1005191.
  • Reiter S., Rodriguez C.C., Sun K. and M. Stopfer. 2015. Spatiotemporal Coding of Individual Chemicals by the Gustatory System. J Neurosci. 35(35): 12309–12321. doi: 10.1523/JNEUROSCI.3802-14.2015
  • Vullhorst D., Mitchell R.M., Keating C., Roychowdhury S., Karavanova I., Tao-Cheng J.H. and A. Buonanno. 2015. A negative feedback loop controls NMDA receptor function in cortical interneurons via neuregulin 2/ErbB4 signalling. Nat Commun. 6:7222. doi: 10.1038/ncomms8222.
  • Xekouki P., Szarek E., Giubellino A., Nesterova M., Rentia N., Dye L., London E., Mastroyannis A., Mastorakos P., Sierra M., Gourgari E., Lyssikatos C., Maher L., Pacak K., Eng C. and C.A. Stratakis. 2015. 3P syndrome (3PS; pituitary adenoma, paraganglioma and/or pheochromocytoma) is due mostly to succinate dehydrogenase defects: human studies and investigation of the pituitary gland in Sdhb+/- mice. J Clin Endocrinol Metab. 100(5): E710–E719.
  • Xie Y., Zhou B., Lin M.Y., Wang S., Foust K.D. and Z.H. Sheng. 2015. Endolysosomal Deficits Augment Mitochondria Pathology in Spinal Motor Neurons of Asymptomatic fALS Mice. Neuron. 87: 355-370. doi: 10.1016/j.neuron.2015.06.026.
  • Yi L. and S.G. Kaler. 2015. Direct interactions of adaptor protein complexes 1 and 2 with the copper transporter ATP7A mediate its anterograde and retrograde trafficking. Hum Mol Genet. 24: 2411-2425. doi: 10.1093/hmg/ddv002. Epub 2015 Jan 7.

2014

  • Bojjireddy N., Botyanszki J., Hammond G., Creech D., Peterson R., Kemp D.C., Snead M., Brown R., Morrison A., Wilson S., Harrison S., Moore C. and T. Balla. 2014. Pharmacological and genetic targeting of the PI4KA enzyme reveals its important role in maintaining plasma membrane phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate levels. J Biol Chem. 289: 6120-6132.
  • Cheng Y., Rodriguiz R.M, Murthy S.R.K., Senatorov V., Thouennon E., Cawley N.X., Aryal D.K., Ahn S., Lecka-Czernik B., Wetsel W.C. and Y.P. Loh. 2014. Neurotrophic factor-α1 prevents stress-induced depression through enhancement of neurogenesis and is activated by rosiglitazone. Molecular Psychiatry 1–11.
  • D'Souza K., Kim Y.J., Balla T. and R.M. Epand. 2014. Distinct properties of the two isoforms of CDP-diacylglycerol synthase. Biochemistry. 53: 7358-7367. Epub 2014 Nov 14.
  • Farber C.R., Reich A., Barnes A.M., Becerra P., Rauch F., Cabral W.A., Bae A., Quinlan A., Glorieux F.H., Clemens T.L. and J.C. Marini. 2014. A novel IFITM5 mutation in severe atypical osteogenesis imperfecta type VI impairs osteoblast production of pigment epithelium-derived factor. J Bone Miner Res. 29: 1402-1411.
  • Guzmán-Hernández M.L., Potter G., Egervári K., Kiss J.Z. and T. Balla. 2014. Secretion of VEGF-165 has unique characteristics, including shedding from the plasma membrane. Mol Biol Cell. 25: 1061-1072.
  • Hammond G.R., Machner M.P. and T. Balla. 2014. A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi. J. Cell. Biol. 205: 113-126.
  • Jovic M., Kean M.J., Dubankova A., Boura E., Gingras A.C., Brill J.A. and T. Balla. 2014. Endosomal sorting of VAMP3 is regulated by PI4K2A. J Cell Sci. 127: 3745-3756. Epub 2014 Jul 7.
  • Lin L., Long L.K., Hatch M.M and D.A. Hoffman. 2014. DPP6 domains responsible for its localization and function. J Biol.Chem.pii: jbc.M114.578070. [Epub ahead of print]
  • Swift M.R., Pham V.N., Castranova D., Bell K., Poole R.J. and B.M. Weinstein. 2014. SoxF factors and Notch regulate nr2f2 gene expression during venous differentiation in zebrafish. Dev Biol. 390: 116-125.
  • Wang H., Kane A.W., Lee C. and S. Ahn. 2014. Gli3 repressor controls cell fates and cell adhesion for proper establishment of neurogenic niche. Cell Rep. 8: 1093-1104.

2013

  • Barnes A.M., Duncan G., Weis M., Paton W., Cabral W.A., Mertz E.L., Makareeva E., Gambello M.J., Lacbawan F.L., Leikin S., Fertala A., Eyre D.R., Bale S.J. and J.C. Marini. 2013. Kuskokwim Syndrome, a Recessive Congenital Contracture Disorder, Extends the Phenotype of FKBP10 Mutations. Hum Mutat. 34: 1279-1288.
  • Campanac E. and D.A. Hoffman. 2013. Repeated cocaine exposure increases fast-spiking interneuron excitability in the rat medial prefrontal cortex. J Neurophysiol. 109: 2781-2792.
  • Cruz-Garcia D., Ortega-Bellido M., Scarpa M., Villeneuve J., Jovic M., Porzner M., Balla T., Seufferlein T. and V. Malhotra. 2013. Recruitment of arfaptins to the trans-Golgi network by PI(4)P and their involvement in cargo export. EMBO J. 32: 1717-29.
  • Haddad M.R., Donsante A., Zerfas P. and S.G. Kaler. 2013. Fetal Brain-directed AAV Gene Therapy Results in Rapid, Robust, and Persistent Transduction of Mouse Choroid Plexus Epithelia. Mol Ther Nucleic Acids. Jun 25;2:e101. doi: 10.1038/mtna.2013.27.
  • Hayes L., Ralls S., Wang H. and S. Ahn. 2013. Duration of Shh signaling contributes to mDA neuron diversity. S. Dev Biol. 374: 115-126.
  • Khadra A., Tomic M., Yan Z., Zemkova H., Sherman A. and S.S. Stojilkovic. 2013. .Dual gating mechanism and function of P2X7 receptor channels. Biophys J. 104: 2612-2621.
  • Kucka M., Bjelobaba I., Clokie S.J., Klein D.C. and S.S. Stojilkovic. 2013. Female-specific induction of rat pituitary dentin matrix protein-1 by GnRH. Mol Endocrinol. 27: 1840-1855.
  • Kong E., Peng S., Chandra G., Sarkar C., Zhang Z., Bagh M.B. and A.B. Mukherjee. 2013. Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43. J Biol Chem. 288: 9112-9125.
  • Lin L., Sun W., Throesch B., Kung F., Decoster J.T., Berner C.J., Cheney R.E., Rudy B. and D.A. Hoffman. 2013. DPP6 regulation of dendritic morphogenesis impacts hippocampal synaptic development. Nat Commun. 4: 2270. doi: 10.1038/ncomms3270
  • Lou H., Park J.J., Phillips A. and Y.P. Loh. 2013. γ-Adducin promotes process outgrowth and secretory protein exit from the Golgi apparatus.. J Mol Neurosci. 49: 1-10.
  • Sarkar C., Chandra G., Peng S., Zhang Z., Liu A., A. Mukherjee: 2013. Neuroprotection and lifespan extension in Ppt1-/- mice by NtBuHa: therapeutic implications for INCL. Nature Neuroscience (Articles).
  • Subramanian J, Dye, L., Morozov A. 2013. Rap1 signaling prevents L type calcium channel dependent neurotransmitter release. J Neuroscience. 33: 7245-7252.

2012

  • Ball, E., Matsuda, M., Dye, L., Hoffman, V., Zerfas, P., Szarek, E., Rich, A., Chitnis, A., and C. Stratakis. 2012. Ultra-structural identification of interstitial cells of Cajalin the zebrafishDaniorerio. Cell and Tissue Research. 349: 483-491
  • Barnes A.M., Cabral W.A., Weis M., Makareeva E., Mertz E.L., Leikin S., Eyre D., Trujillo C. and J.C. Marini. 2012. Absence of FKBP10 in recessive type XI osteogenesis imperfecta leads to diminished collagen cross-linking and reduced collagen deposition in extracellular matrix. Hum Mutat. doi: 10.1002/humu.22139. [Epub ahead of print]
  • Gupta N. and M. Stopfer. 2012. Functional analysis of a higher olfactory center, the lateral horn. J. Neurosci. 32: 8138-8148.
  • Hammond G.R., Fischer M.J., Anderson K.E., Holdich J., Koteci A., Balla T. and R.F. Irvine. 2012. PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity. Science. 337: 727-730.
  • Huang F.L. and K. P. Huang. 2012. Methylphenidate improves the behavioral and cognitive deficits of neurogranin knockout mice. Genes Brain Behav. 2012 Jul 18. doi: 10.1111/j.1601-183X.2012.00825.x. [Epub ahead of print]
  • Jovic M., Kean M.J., Szentpetery Z., Polevoy G., Gingras A.C., Brill J.A. and T. Balla. 2012. Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, β-glucocerebrosidase. Mol. Biol. Cell. 23: 1533-1545.
  • Lopez C.M., Pelkey K.A., Chittajallu R., Nakashiba T., Tóth K., Tonegawa S.and C.J. McBain. 2012. Competition from newborn granule cells does not drive axonal retraction of silenced old granule cells in the adult hippocampus. Front Neural Circuits. 2012;6:85. doi: 10.3389/fncir.2012.00085.
  • Lou H., Park J.J., Phillips A. and Y.P. Loh. 2012. γ-Adducin Promotes Process Outgrowth and Secretory Protein Exit from the Golgi Apparatus. J Mol Neurosci. [Epub ahead of print]
  • Nestor M.W. and D.A. Hoffman. 2012. Differential cycling rates of Kv4.2 channels in proximal and distal dendrites of hippocampal CA1 pyramidal neurons. Hippocampus. 22: 969-980.
  • Ochocinska M.J., Muñoz E.M., Veleri S., Weller J.L., Coon S.L., Pozdeyev N., Michael Iuvone P., Goebbels S., Furukawa T. and D.C. Klein. 2012. NeuroD1 is required for survival of photoreceptors but not pinealocytes: Results from targeted gene deletion studies. Journal of Neurochemistry. (Epub ahead of print)
  • Takagi M., Ishii T., Barnes A.M., Weis M., Amano N., Tanaka M., Fukuzawa R., Nishimura G., Eyre D.R., Marini J.C., and T. Hasegawa T. 2012. A novel mutation in LEPRE1 that eliminates only the KDEL ER- retrieval sequence causes non-lethal osteogenesis imperfecta. PLoS One. 7(5):e36809. Epub 2012 May 15.
  • Tanaka N., Suzuki, E., Dye, L., Ejima, A., and M. Stopfer. 2012. Dye-fills reveal additional olfactory tracts in the protocerebrum of wild-type Drosophila. Journal of Comparative Neurology. 520: 4131-4140.
  • Yi L., Donsante A., Kennerson M.L., Mercer J.F., Garbern J.Y. and S.G. Kaler. 2012. Altered intracellular localization and valosin-containing protein (p97 VCP) interaction underlie ATP7A-related distal motor neuropathy. Hum Mol Genet. 2012 Apr 15;21(8):1794-807. Epub 2011 Dec 30.

2011

  • Cawley N.X., Portela-Gomes G., Lou H. And Y.P. Loh. 2011. Yapsin 1 immunoreactivity in alpha cells of human pancreatic islets: implications for the processing of human proglucagon by mammalian aspartic proteases. J Endocrinol. 210: 181-187.
  • Cea-del Rio C.A., Lawrence J.J., Erdelyi F., Szabo G. and C.J. McBain. 2011. Cholinergic modulation amplifies the intrinsic oscillatory properties of CA1 hippocampal cholecystokinin-positive interneurons. J. Physiol. 589: 609-627.
  • Hayes, L., Zhang, Z., Albert, P., Zervas, M., and S. Ahn. 2011. The timing of Sonic hedgehog and Gli1 expression segregates midbrain dopamine neurons, J Comp Neurol 519, 3001-3018.
  • Huang K.P., Huang F.L. and P.K. Shetty. 2011. Stimulation-mediated translocation of calmodulin and neurogranin from soma to dendrites of mouse hippocampal CA1 pyramidal neurons. Neuroscience. 2011. Jan 20. [Epub ahead of print]
  • Huang K.P. and F.L. Huang. 2011. Calcium-Sensitive Translocation of Calmodulin and Neurogranin between Soma and Dendrites of Mouse Hippocampal CA1 Neurons. A.C.S. Chem. Neurosci. 2: 223-230.
  • Kim Y.J., Guzman-Hernandez M.L. and T. Balla. 2011. A highly dynamic ER-derived phosphatidylinositol-synthesizing organelle supplies phosphoinositides to cellular membranes. Dev. Cell. 21: 813-824.
  • Komlosh M.E., Özarslan E., Lizak M.J., Horkay F., Schram V., Shemesh N., Cohen Y. and P.J. Basser. 2011. Pore diameter mapping using double pulsed-field gradient MRI and its validation using a novel glass capillary array phantom. J. Magn. Reson. 208: 128-135.
  • Li S., Bjelobaba I., Yan Z., Kucka M., Tomic M. and S.S. Stojilkovic. 2011. Expression and roles of pannexins in ATP release in the pituitary gland. Endocrinology. 152: 2342-2352.
  • Liu M. and M.V. Eiden. 2011. The receptors for gibbon ape leukemia virus and amphotropic murine leukemia virus are not down-regulated in productively infected cells. Retrovirology. 5: 8:53.
  • Liu X.H., Xu W., Russ J., Eiden L.E. and M.V. Eiden. 2011. The host range of gammaretroviruses and gammaretroviral vectors includes post-mitotic neural cells. PLoS One. 6:e18072
  • Neddens J., Fish K.N., Tricoire L., Vullhorst D., Shamir A., Chung W., Lewis D.A., McBain C.J. and A. Buonanno. 2011. Conserved Interneuron-Specific ErbB4 Expression in Frontal Cortex of Rodents, Monkeys, and Humans: Implications for Schizophrenia. Biol. Psychiatry. [Epub ahead of print].
  • Nestor M.W. and D.A. Hoffman. 2011. Differential cycling rates of Kv4.2 channels in proximal and distal dendrites of hippocampal CA1 pyramidal neurons. Hippocampus. doi: 10.1002.
  • Park J.J., Gondré-Lewis M.C., Eiden L.E. and Y.P. Loh. 2011. A distinct trans-Golgi network subcompartment for sorting of synaptic and granule proteins in neurons and neuroendocrine cells. J. Cell. Sci. 124: 735-744.
  • Park JJ, Loh YP. 2011. Visualization of peptide secretory vesicles in living nerve cells. Methods Mol Biol. 789: 137-145.
  • Sarkar C., Zhanga Z. and A.B. Mukherjee. 2011. Stop codon read-through with PTC124 induces palmitoyl-protein thioesterase-1 activity, reduces thioester load and suppresses apoptosis. Mol. Genet. Metab. doi:10.1016/j.ymgme.2011.05.021
  • Subramanian J. and A. Morozov. 2011. Erk1/2 inhibit synaptic vesicle exocytosis through L-type calcium channels. J Neurosci. 31: 4755-4764.
  • Tanaka N.K., Dye L. and M.J. Stopfer. 2011. Dual-labeling method for electron microscopy to characterize synaptic connectivity using genetically encoded fluorescent reporters in Drosophila. Neurosci. Methods. 194: 312-315.
  • Tricoire L., Pelkey K.A., Erkkila B.E., Jeffries B.W., Yuan X. and C.J. McBain. 2011. A blueprint for the spatiotemporal origins of mouse hippocampal interneuron diversity. J. Neurosci. 31: 10948-10970.
  • Valli M., Barnes A.M., Gallanti A., Cabral W., Viglio S., Weis M., Makareeva E., Eyre D., Leikin S., Antoniazzi F., Marini J.C. and M. Mottes. 2011. Deficiency of CRTAP in non-lethal recessive osteogenesis imperfecta reduces collagen deposition into matrix. Clin Genet. 2011 Sep 28. doi: 10.1111/j.1399-0004.2011.01794.x. [Epub ahead of print]
  • Wang, H., Ge, G., Uchida, Y., Luu, B., and S. Ahn. 2011. Gli3 is required for maintenance and fate specification of cortical progenitors, J Neurosci 31, 6440-6448.
  • Wang P.M., Kachel D.L., Cesta M.F. and W.J. Martin. 2011. Direct leukocyte migration across pulmonary arterioles and venules into the perivascular interstitium of murine lungs during bleomycin injury and repair. Am. J. Pathol. 178: 2560-2572.
  • Wei H., Zhang Z., Saha A., Peng S., Chandra G., Quezado Z. and A.B. Mukherjee. 2011. Disruption of adaptive energy metabolism and elevated ribosomal p-S6K1 levels contribute to INCL pathogenesis: partial rescue by resveratrol. Hum. Mol. Genet. 20: 1111-1121.

2010

  • Barnes A.M., Carter E.M., Cabral W.A., Weis M., Chang W., Makareeva E., Leikin S., Rotimi C.N., Eyre D.R., Raggio C.L. and J.C. Marini. 2010. Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding. New Engl. J. Med. 362: 521-528.
  • Cea-del Rio C.A., Lawrence J.J., Tricoire L., Erdelyi F., Szabo G. and C.J. McBain. 2010. M3 muscarinic acetylcholine receptor expression confers differential cholinergic modulation to neurochemically distinct hippocampal basket cell subtypes. J. Neurosci. 30: 6011-6024.
  • Chang W., Barnes A.M., Cabral W.A., Bodurtha J.N. and J.C. Marini. 2010. Prolyl 3-hydroxylase 1 and CRTAP are mutually stabilizing in the endoplasmic reticulum collagen prolyl 3-hydroxylation complex. Hum. Mol. Genet. 19: 223-234.
  • Han S., Makareeva E., Kuznetsova N.V., DeRidder A.M., Sutter M.B., Losert W., Phillips C.L., Visse R., Nagase H. and S. Leikin. 2010. Molecular mechanism of type I collagen homotrimer resistance to mammalian collagenases. J. Biol. Chem. 285: 22276-22281.
  • Kino T., Hurt D.E., Ichijo T., Nader N. and G.P. Chrousos. 2010. Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor. Sci. Signal. 3: 1-7.
  • Korzeniowski M.K., Manjarrés I.M., Varnai P. and T. Balla. 2010. Activation of STIM1-Orai1 involves an intramolecular switching mechanism. Sci. Signal. 3: ra82.
  • Koshimizu H., Kim T., Cawley N.X. and Y.P. Loh. 2010. Chromogranin A: a new proposal for trafficking, processing and induction of granule biogenesis. Regul. Pept. 160: 153-159.
  • Lee T.K., Murthy S.R., Cawley N.X., Dhanvantari S., Hewitt S.M., Lou H., Lau T., Ma S., Huynh T., Wesley R.A., Ng I.O., Pacak K., Poon R.T. and Y.P. Loh. 2010. An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers. J. Clin. Invest. doi: 10.1172 / JCI40433.
  • Lin L., Sun W., Wikenheiser A.M., Kung F. and D.A. Hoffman. 2010. KChIP4a regulates Kv4.2 channel trafficking through PKA phosphorylation. Mol. Cell. Neurosci. 43: 315-325.
  • Lou H., Park J.J., Cawley N.X., Sarcon A., Sun L., Adams T. and Y.P. Loh. 2010. Carboxypeptidase E cytoplasmic tail mediates localization of synaptic vesicles to the pre-active zone in hypothalamic pre-synaptic terminals. J. Neurochem. 114: 886-896.
  • Nader N., Bachrach B.E., Hurt D.E., Gajula S., Pittman A., Lescher R. and T. Kino. 2010. A novel point mutation in helix 10 of the human glucocorticoid receptor causes generalized glucocorticoid resistance by disrupting the structure of the ligand-binding domain. J. Clin. Endocrinol. Metab. 95: 2281-2285.
  • Neddens J. and A. Buonanno. 2010. Selective populations of hippocampal interneurons express ErbB4 and their number and distribution is altered in ErbB4 knockout mice. Hippocampus. 20: 724-744.
  • Saha A., Lee Y.C., Zhang Z., Chandra G., Su S.B. and A.B. Mukherjee. 2010. Lack of an endogenous anti-inflammatory protein in mice enhances colonization of B16F10 melanoma cells in the lungs. J. Biol. Chem. 285: 10822-10831.
  • Shamir A. and A. Buonanno. 2010. Molecular and cellular characterization of Neuregulin-1 type IV isoforms. J. Neurochem. 113: 1163-1176.
  • Szentpetery Z., Várnai P. and T. Balla. 2010. Acute manipulation of Golgi phosphoinositides to assess their importance in cellular trafficking and signaling.Proc. Natl. Acad. Sci. USA. 107: 8225-8230.
  • Tricoire L., Pelkey K.A., Daw M.I., Sousa V.H., Miyoshi G., Jeffries B., Cauli B., Fishell G. and C.J. McBain. 2010. Common origins of hippocampal Ivy and nitric oxide synthase expressing neurogliaform cells. J. Neurosci. 30: 2165-2176.

2009

  • Atkin S.D., Patel S., Kocharyan A., Holtzclaw L.A., Weerth S.H., Schram V., Pickel J. and J.T. Russell. 2009. Transgenic mice expressing a cameleon fluorescent Ca2+ indicator in astrocytes and Schwann cells allow study of glial cell Ca2+ signals in situ and in vivo. J. Neurosci. Methods. 181: 212-226.
  • Balla T. and Várnai P. 2009. Visualization of cellular phosphoinositide pools with GFP-fused protein-domains. Curr. Protoc. Cell. Biol. 24: 24-44.
  • Besser L., Chorin E., Sekler I., Silverman W.F., Atkin S., Russell J.T. and M. Hershfinkel. 2009. Synaptically released zinc triggers metabotropic signaling via a zinc-sensing receptor in the hippocampus. J. Neurosci. 29: 2890-2901.
  • Campa F., Yoon H.Y., Ha V.L., Szentpetery Z. and T. Balla. 2009. A pH domain in the Arf GTPase-activating protein (GAP) ARAP1 binds phosphatidylinositol 3,4,5-trisphosphate and regulates Arf GAP activity independently of recruitment to the plasma membranes. J. Biol. Chem. 284: 28069-28083.
  • Daw M.I., Tricoire L., Erdelyi F., Szabo G. and C.J. McBain. 2009. Asynchronous transmitter release from cholecystokinin-containing inhibitory interneurons is widespread and target-cell independent. J. Neurosci. 29: 11112-11122.
  • Fisahn A., Neddens J., Yan L. and A. Buonanno. 2009. Neuregulin-1 modulates hippocampal gamma oscillations: implications for schizophrenia. Cereb. Cortex. 19: 612-618.
  • Hwang Y.S., Luo T., Xu Y. and T.D. Sargent. 2009. Myosin-X is required for cranial neural crest cell migration in Xenopus laevis. Dev. Dyn. 238: 2522-2529.
  • Ito I., Bazhenov M., Ong R.C., Raman B. and M. Stopfer. 2009. Frequency transitions in odor-evoked neural oscillations. Neuron. 64: 692-706.
  • Kino T., Manoli I., Kelkar S., Wang Y., Su Y.A. and G.P. Chrousos. 2009. Glucocorticoid receptor (GR) Beta has intrinsic, GRa-independent transcriptional activity. Biochem. Biophys. Res. Com. 381: 671--675.
  • Korzeniowski M.K., Szanda G., Balla T and A. Spät. 2009. 2009. Store-operated Ca2+ influx and subplasmalemmal mitochondria. Cell Calcium. 46: 49-55.
  • Koshimizu H., Senatorov V, Loh Y.P. and I. Gozes. 2009. Neuroprotective protein and carboxypeptidase E. J. Mol. Neurosci. 39: 1-8.
  • Ma H., Blake T., Chitnis A., Liu P. and T. Balla. 2009. Crucial role of phosphatidylinositol 4-kinase III alpha in development of zebrafish pectoral fin is linked to phosphoinositide 3-kinase and FGF signaling. J. Cell Sci. 122: 4303-4310.
  • Neddens J. and A. Buonanno. 2009. Selective populations of hippocampal interneurons express ErbB4 and their number and distribution is altered in ErbB4 knockout mice. Hippocampus.
  • Park J.J., Koshimizu H. and Y.P. Loh. 2009. Biogenesis and transport of secretory granules to release site in neuroendocrine cells. J. Mol. Neurosci. 37: 151-159.
  • Rafikova E., Melikov K., Ramos C., Dye L. and L. Chernomordik. 2009. Transmembrane protein-free membranes fuse into Xenopus nuclear envelope and promote assembly of functional pores. J. Biol. Chem. 284: 29847-29859.
  • Samoshkin S., Arnaoutov A., Jansen L., Ouspenski I., Dye L., Karpova T., McNally J., Dasso M., Cleveland D. and A. Strunnikov. 2009. Human Condensin Function Is Essential for Centromeric Chromatin Assembly and Proper Sister Kinetochore Orientation. PLoS ONE 4: e6831.
  • Szentpetery Z., Balla A., KimY.J., Lemmon M.A. and T. Balla. 2009. Live cell imaging with protein domains capable of recognizing phosphatidylinositol 4,5-bisphosphate; a comparative study. BMC Cell Biology, 10: 67-87.
  • Tanaka N., Ito K., and M. Stopfer. 2009. Odor-Evoked Neural Oscillations in Drosophila Are Mediated by Widely Branching Interneurons. The Journal of Neuroscience. 29: 8595-8603.
  • Uveges T.E., Kozloff K.M., Ty J.M., Ledgard F., Raggio C.L., Gronowicz G., Goldstein S.A. and J.C. Marini. 2009. Alendronate Treatment of Brtl Osteogenesis Imperfecta Mouse Improves Femoral Geometry and Load Response Before Fracture but Decreases Predicted Material Properties and Has Detrimental Effects on Osteoblasts and Bone Formation. J. Bone Miner. Res. 24: 849-859.
  • Vullhorst D., Neddens J., Karavanova I., Tricoire L., Petralia R.S., McBain C.J. and A. Buonanno. 2009. Selective expression of ErbB4 in interneurons, but not pyramidal cells, of the rodent hippocampus. J. Neurosci. 29: 12255-12564.
  • Wollert T., Wunder C., Lippincott-Schwartz J. and J.H. Hurley. 2009. Membrane scission by the ESCRT-III complex. Nature. 458: 172-177.

2008

  • Arnaoutova I., Cawley N.X., Patel N., Kim T., Rathod T. and Y.P. Loh. 2008. Aquaporin 1 is important for maintaining secretory granule biogenesis in endocrine cells. Mol. Endocrinol. 22: 1924-1934.
  • Baldwin G.S., Nicholas J.B., Robson R.E., Wynveen A., Goldar A., Leikin S., Seddon J.M. and A.A. Kornyshev. 2008. DNA Double Helices Recognize Mutual Sequence Homology in a Protein Free Environment. J. Phys. Chem. B, 112: 1060-1064.
  • Balla A., Kim Y.J., Varnai P., Szentpetery Z., Knight Z., Shokat K.M. and T. Balla. 2008. Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase III alpha. Mol. Biol. Cell. 19: 711-721.
  • Gore A.V., Lampugnani, M.G., Dye L., Dejana, E. and B. Weinstein. 2008. Combinatorial interaction between CCM pathway genes precipitates hemorrhagic stroke. Dis. Model Mech. 1: 275--281.
  • Han S., McBride D.J., Losert W. and S. Leikin. 2008. Segregation of type I collagen homo- and heterotrimers in fibrils. J. Mol. Biol. 383: 122-132.
  • Ito I., Ong R.C., Raman B. and M. Stopfer. 2008. Sparse odor representation and olfactory learning. Nat. Neurosci. 11: 1177-1184.
  • Jung S.C., Kim J. and D.A. Hoffman. 2008. Rapid, bidirectional remodeling of synaptic NMDA receptor subunit composition by A-type K+ channel activity in hippocampal CA1 pyramidal neurons. Neuron. 60: 657-671.
  • Kim S.J., Zhang Z., Sarkar C., Tsai, P.C., Lee Y.C., Dye L. and A. Mukherjee. 2008. Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice. J. Clin. Investigation. 118: 3075-3086.
  • Kwon O.B., Paredes D., Gonzalez C.M., Neddens J., Hernandez L., Vullhorst D. and A. Buonanno. 2008. Neuregulin-1 regulates LTP at CA1 hippocampal synapses through activation of dopamine D4 receptors. Proc. Natl. Acad. Sci. 105: 15587-15592.
  • Park J.J., Cawley N.X. and Y.P. Loh. 2008. Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. Mol. Endocrinol. 22: 989-1005.
  • Park J.J., Cawley N.X. and Y.P. Loh. 2008. A bi-directional carboxypeptidase E-driven transport mechanism controls BDNF vesicle homeostasis in hippocampal neurons. Mol. Cell Neurosci. 39: 63-73.
  • Porrás A., Kozar S., Russanova V., Salpea P., Hirai T., Sammons N., Mittal P., Kim J.Y., Ozato K., Romero R. and B.H. Howard. 2008. Developmental and epigenetic regulation of the human TLR3 gene. Mol. Immunol. 46: 27-36.
  • Stefanovic B., Hutchinson E., Yakovleva V., Schram V., Russell J.T., Belluscio L., Koretsky A.P. and A.C. Silva. 2008. Functional reactivity of cerebral capillaries. J. Cereb. Blood Flow Metab. 28: 961-972.
  • Szaszák M., Chen H.D., Chen H.C., Baukal A., Hunyady L. and K.J.J Catt. 2008. Identification of the invariant chain (CD74) as an angiotensin AGTR1-interacting protein. Endocrinol. 199: 165-176.
  • Woronowicz A., Koshimizu H., Chang S.Y., Cawley N.X., Hill J.M., Rodriguiz R.M., Abebe D., Dorfman C., Senatorov V., Zhou A., Xiong Z.G.,
  • Wetsel W.C. and Y.P. Loh. 2008. Absence of carboxypeptidase E leads to adult hippocampal neuronal degeneration and memory deficits. Hippocampus. 18: 1051-1063.
  • Zemkova H.W., Bjelobaba I., Tomic M., Zemkova H. and S.S. Stojilkovic.2008. Molecular, pharmacological and functional properties of GABAA receptors in anterior pituitary cells. J. Physiol 586: 3097--3111.

2007

  • Forlino A., Kuznetsova N.V., Marini J.C. and S. Leikin. 2007. Selective retention and degradation of molecules with a single mutant alpha1(I) chain in the Brtl IV mouse model of OI. Matrix Biol. 26: 604-614.
  • Hatae N., Aksentijevich N., Zemkova H.W., Kretschmannova K., Tomic M. and S.S. Stojilkovic. 2007. Cloning and functional identification of novel endothelin receptor type A isoforms in pituitary. Mol. Endocrinol. 21: 1192-1204.
  • Karavanova I., Vasudevan K., Cheng J. and A. Buonanno. 2007. Novel regional and developmental NMDA receptor expression patterns uncovered in NR2C subunit-beta-galactosidase knock-in mice. Mol. Cell. Neurosci. 34: 468-480.
  • Kim J., Jung S.C., Clemens A., Petralia R. and D. Hoffman. 2007. Regulation of dendritic excitability by activity-dependent trafficking of the A-type K+ channel subunit Kv4.2 in hippocampal neurons. Neuron. 54: 933-947
  • Lou H., Smith A.M., Coates L.C., Cawley N.X. and Y.P. Loh. 2007. The transmembrane domain of the prohormone convertase PC3: A key motif for targeting to the regulated secretory pathway. Molecular and Cellular Endocrinology. 267: 17-25.
  • Luo T., Xu Y., Hoffman T.L., Zhang T., Schilling T. and T.D. Sargent. 2007. Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development. Development. 134: 1279-1289.
  • Ong H.L., Liu X., Tsaneva-Atanasova K., Singh B.B., Bandyopadhyay B.C., Swaim W.D., Russell J.T., Hegde R.S., Sherman A. and I.S. Ambudkar. 2007. Relocalization of STIM1 for activation of store-operated Ca(2+) entry is determined by the depletion of subplasma membrane endoplasmic reticulum Ca(2+) store. J. Biol. Chem. 282: 12176-12185.
  • Ong H.L., Liu X., Sharma A., Hegde R.S. and I.S. Ambudkar. 2007. Intracellular Ca(2+) release via the ER translocon activates store-operated calcium entry. Pflugers Arch. 453: 797-808.
  • Pelkey K.A, Yuan X., Lavezzari G., Roche K.W. and C.J. McBain. 2007. mGluR7 undergoes rapid internalization in response to activation by the allosteric agonist AMN082. Neuropharmacology. 52: 108-117.
  • Pham V.N., Lawson N.D., Mugford G.W., Dye L., Castranova D., Loa B. and B.M. Weinstein. 2007. Combinatorial function of ETS transcription factors in the developing vasculature. Dev. Bio.303: 772-783.
  • Toews J., Schram V., Weerth S.H., Mignery G.A. and J.T. Russell. 2007. Signaling proteins in the axoglial apparatus of sciatic nerve nodes of Ranvier. Glia 55: 202-213.
  • van de Leemput J., Chandran J., Knight M.A., Holtzclaw L.A., Scholz S., Cookson M.R., Houlden H., Gwinn-Hardy K., Fung H.C., Lin X., Hernandez D., Simon-Sanchez J., Wood N.W., Giunti P., Rafferty I., Hardy J., Storey E., Gardner R.J., Forrest S.M., Fisher E.M., Russell J.T., Cai H. and A.B. Singleton. 2007. Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans. PLoS Genet. 3: e108.
  • Várnai P., Tóth B., Tóth D.J., Hunyady L. and T. Balla. 2007. Visualization and manipulation of plasma membrane-endoplasmic reticulum contact sites indicates the presence of additional molecular components within the STIM1-Orai1 Complex. J. Biol. Chem. 282: 29678-29690.
  • Vermeire K., Lisco A., Grivel J.C., Scarbrough E., Dey K., Duffy N., Margolis L., Bell T.W. and D. Schols. Design and cellular kinetics of dansyl-labeled CADA derivatives with anti-HIV and CD4 receptor down-modulating activity. Biochem Pharmacol. 74: 566-578.
  • Weerth SH, Holtzclaw LA and J.T. Russell. 2007. Signaling proteins in raft-like microdomains are essential for Ca2+ wave propagation in glial cells. Cell Calcium. 41: 155-167.
  • Yagi R., Kohn M.J., Karavanova I., Kaneko K.J., Vullhorst D., DePamphilis M.L. and A. Buonanno. 2007. Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development. Development. 134: 3827-3836.
  • Zemkova H., Yan Z., Liang Z., Jelinkova I., Tomic M. and S.S. Stojilkovic. 2007. Role of aromatic and charged ectodomain residues in the P2X(4) receptor functions. J. Neurochem. 102: 1139-1150.

2006

  • Balazs T., Ball A., Ma H., Knight Z.A., Shokat K.M. and T. Balla. 2006. Phosphatidylinositol 4-kinase regulates the transport of ceramide between the endoplasmic reticulum and golgi. J. Biol. Chem. (In Press).
  • Gondre-Lewis, M., Petrache, H., Wassif, C., Harries, D., Parsegian, A., Porter, F. and Y.P. Loh. 2006 Abnormal sterols cause secretory granule malformation in cholesterol deficiency diseases and decreased membrane curvature. J. Cell Science. 119: 1876-1885.
  • Kamei M, Saunders B, Bayless K, Dye L, Davis G and B. Weinstein. 2006. Endothelial tubes assemble from intracellular vacuoles in vivo. Nature 442: 6554-6559.
  • Kim, T., Gondre-Lewis, M., Arnaoutova, I. And Y.P. Loh. 2006. Dense-core Secretory Granule Biogenesis. Physiology 21: 124-133.
  • Kim T. and Y.P. Loh. 2006. Protease Nexin-1 regulates granule protein stability and secretory granule biogenesis at the golgi. Mol. Biol. Cell. 17: 789-798.
  • Mavrakis, M., Lippincott-Schwartz, J., Stratakis, C.A., and I. Bossis. 2006. Depletion of type IA regulatory subunit (RIa) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency. Human Molecular Genetics 15: 2962-2971.
  • Odling K., Albertsson C., Russell J.T. and L.G. Mårtensson. 2006. An in vivo study of exocytosis of cement proteins from barnacle Balanus improvisus (D.) cyprid larva. J. Exp. Biol. 209: 956-964.
  • Pelkey K.A., Yuan X.-Q., Lavezzari G., Roche K.W. and J.C. McBain. 2006. mGluR7 undergoes rapid internalization in response to activation by the allosteric agonist AMN082. Neuropharmacology 52: 108-117.
  • Plosky B.S., Vidal A.E., Henestrosa A.R.F., McLenigan M.P., McDonald J.P., Mead S. and R. Woodgate. 2006. Controlling the subcellular localization of DNA polymerases i and g via interactions with ubiquitin. EMBO J. 25: 2847--2855.
  • Varnai P., Thyagarajan B., Rohacs T. and T. Balla. 2006. Rapidly inducible changes in phosphatidylinositol 4,5-biphosphate levels influence multiple regulatory functions of the lipid in intact living cells. J. Cell Biol. 175: 377-382.
  • Yan Z., Liang Z., Obsil T. and S.S. Stojilkovic SS. 2006. Participation of the lys313-ile333 sequence of the P2X4 receptor in agonist binding and transduction of signals to the channel gate. J Biol Chem 281: 32649-32659.
  • Yaniv K., Isogai S., Castranova D., Dye L., Hitomi J. and B.M. Weinstein. 2006. Live imaging of lymphatic development in the zebrafish. Nature Medicine (12, 711-716.).
  • Yanik T., Dominguez G., Kuhar M.J., Del Giudice E.M. and Y.P. Loh. 2006. The Leu34Phe ProCART mutation leads to cocaine- and amphetamine-regulated transcript (CART) deficiency: a possible cause for obesity in humans. Endocrinology. 147: 39-43.

2005

  • Kim T., Zhang C.F., Sun Z., Wu H. and Y.P. Loh. 2005. Chromogranin A deficiency in transgenic mice leads to aberrant chromaffin granule biogenesis. J. Neurosci. 25: 6958-6961.
  • Kino T., Tiulpakov A., Ichijo T., Chheng L., Kozasa T. and G.P. Chrousos. 2005. G protein beta interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus. J. Cell Biol. 169: 885-896.
  • Kino T., Kozasa T. and G.P. Chrousos. 2005. Statin-induced blockade of prenylation alters nucleocytoplasmic shuttling of GTP-binding proteins gamma2 and beta2 and enhances their suppressive effect on glucocorticoid receptor transcriptional activity. Eur. J. Clin. Invest. 35: 508-513.
  • Kwon O.B., Longart M., Vullhorst D., Hoffman D.A. and A. Buonanno. 2005. Neuregulin-1 reverses long-term potentiation at CA1 hippocampal synapses. J. Neurosci. 25: 9378-9383.
  • Mavrakis M., Lippincott-Schwartz J., Stratakis C.A. and I. Bossis. 2006. Depletion of type IA regulatory subunit (RIa) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency. Human Molecular Genetics 15: 2962-2971.
  • Olivares-Reyes J.A., Shah B.H., Hernandez-Aranda J., Garcia-Caballero A., Farshori M.P., Garcia-Sainz J.A. and K.J. Catt. 2005. Agonist-induced interactions between angiotensin AT1 and epidermal growth factor receptors. Mol. Pharmacol. 68: 356-364.
  • Sidhu G., Li W., Laryngakis N., Bishai E., Balla T. and F. Southwick. 2005. Phosphoinositide 3-kinase is required for intracellular Listeria monocytogenes actin-based motility and filopod formation. J. Biol. Chem. 280: 11379-11386.
  • Varnai P., Balla A., Hunyady L. and T. Balla. 2005. Targeted expression of the inositol 1,4,5-triphosphate receptor (IP3R) ligand-binding domain releases Ca2+ via endogenous IP3R channels. Proc. Natl. Acad. Sci. USA. 102: 7859-7864.
  • Varnai P., Bondeva T., Tamas P., Toth B., Buday L., Hunyady L. and T. Balla. 2005. Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3,4,5)P3 suggest their interaction with protein binding partners. J. Cell Sci. 118: 4879-4888.
  • Yan Z., Liang Z., Tomic M., Obsil T. and S.S. Stojilkovic. 2005. Molecular determinants of the agonist binding domain of a P2X receptor channel. Mol. Pharmacol. 67: 1078-1088.
  • Zhu X., Wu K., Rife L., Cawley N.X., Brown B., Adams T., Teofilo K., Lillo C., Williams D.S., Loh Y.P. and C.M. Craft. 2005. Carboxypeptidase E is required for normal synaptic transmission from photoreceptors to the inner retina. J Neurochem. 95:1351-1362.

2004

  • Kino T., Liou S.H., Charmandari E. and G.P. Chrousos. 2004. Glucocorticoid receptor mutants demonstrate increased motility inside the nucleus of living cells: time of fluorescence recovery after photobleaching (FRAP) is an integrated measure of receptor function. Mol. Med. 10: 80-88.
  • Tang J., Stern-Nezer S., Liu P.C., Matyakhina L., Riordan M., Luban N.L., Steinbach P.J. and S.G. Kaler. 2004. Mutation in the leucine-rich repeat C-flanking region of platelet glycoprotein Ib beta impairs assembly of von Willebrand factor receptor. Thromb. Haemost. 92: 75-88.
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