If we knew what it was we were doing, it would not be called research, would it?
- Albert Einstein

Current Projects:

Extracellular Matrix Disorders: Molecular Mechanisms and Treatment Targets

• Regulation of collagen synthesis, quality control, trafficking, and degradation in fibroblasts and osteoblasts 
• Osteogenesis Imperfecta: cell culture and mouse models, molecular mechanisms, treatment targets, and development of novel treatments
• Translational and mechanistic studies of collagen and proteoglycan related pathology in other forms of skeletal dysplasia, fibrosis, and cancer 

High-definition micro-spectroscopic imaging and analysis of biomaterials

• Development of high-definition micro-spectroscopic imaging technology
• Real-time, label-free imaging of biochemical reactions in tissue sections and live cell cultures