Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at OPM.gov.

Research

If we knew what it was we were doing, it would not be called research, would it?
- Albert Einstein

Current Projects:

Extracellular Matrix Disorders: Molecular Mechanisms and Treatment Targets

  • Regulation of collagen synthesis, quality control, trafficking, and degradation in fibroblasts and osteoblasts 
  • Osteogenesis Imperfecta: cell culture and mouse models, molecular mechanisms, treatment targets, and development of novel treatments
  • Translational and mechanistic studies of collagen and proteoglycan related pathology in other forms of skeletal dysplasia, fibrosis, and cancer 

High-definition micro-spectroscopic imaging and analysis of biomaterials

  • Development of high-definition micro-spectroscopic imaging technology
  • Real-time, label-free imaging of biochemical reactions in tissue sections and live cell cultures