The NICHD established the MFMU Network in 1986 to respond to the need for well-designed clinical trials in maternal- fetal medicine and obstetrics, particularly with respect to the continuing problem of preterm birth. The aims of the Network are to reduce maternal, fetal, and infant morbidity related to preterm birth, fetal growth abnormalities, and maternal complications, and to provide the rationale for evidence-based, cost-effective obstetric practice.
The Institute funds the MFMU Network through its Pregnancy and Perinatology Branch (PPB) using the Cooperative Clinical Research award mechanism (U10) in 5 -year competitive cycles. For the 2011–2016 cycle, the MFMU Network includes 14 clinical centers at U.S. universities and hospitals, a data coordinating center at T he George Washington University, and the NICHD . MFMU Network centers may include one or more affiliated hospitals. The clinical centers represent premier institutions in perinatal medicine with track records of excellence in clinical research.
The National Heart, Lung, and Blood Institute and the National Institute of Neurological Disorders and Stroke also provide support for certain projects within the MFMU Network.
MFMU Network studies include randomized clinical trials, cohort studies, and registries. Network trials may be found on www.clinicaltrials.gov and on the MFMU Network website .
The MFMU Network has conducted clinical studies related to the following critical areas of research: maternal health; fetal health and development; gestational diabetes, asthma, and thyroid disorders; and preterm labor.Current MFMU Network studies include (but are not limited to) the following:
Current MFMU Network centers include:
The data coordinating center for the MFMU Network is The George Washington University Biostatistics Center.