The CCTN was established in 1996 to support research on male and female contraception and to conduct clinical trials of new contraceptive drugs and devices.
The Network is funded through the NICHD Contraceptive Discovery and Development Branch (CDDB) (formerly the Contraception and Reproductive Health (CRH) Branch and includes 19 sites for clinical evaluation of new female contraceptives and two sites for male contraceptives. Sites are located at university research centers and medical centers across the country. Each site employs a qualified obstetrician/gynecologist (for female-focused sites) or andrologist/urologist (for male-focused sites), study coordinator, and data/research manager, and has access to clinical facilities capable of recruiting for and conducting phase I, II, and III clinical trials.
The Network is funded through contracts and utilizes a Scientific Advisory Committee to advise on research topics and directions. The Scientific Advisory Committee is composed of outside experts in the fields of basic and clinical contraceptive research, pharmacology, and epidemiology. The Network also relies on a Statistical and Clinical Coordinating Center to monitor trials and coordinate data from all of its studies.
The CCTN clinical field centers are selected on the basis of their capacity to conduct Phase I, II, and III trials of oral, vaginal, intrauterine, injectable, implantable, or topical contraceptive drugs and devices.
Selected research topics include (but are not limited to):
Health Decisions, Inc., serves as the Statistical and Clinical Coordinating Center for the CCTN.